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儿童注意力缺陷/多动障碍与酒精依赖:1年随访

Childhood attention deficit/hyperactivity disorder and alcohol dependence: a 1-year follow-up.

作者信息

Ercan Eyüp Sabri, Coşkunol Hakan, Varan Azmi, Toksöz Kaan

机构信息

Department of Child Psychiatry, Ege University, School of Medicine, Bornova, Izmir, Turkey.

出版信息

Alcohol Alcohol. 2003 Jul-Aug;38(4):352-6. doi: 10.1093/alcalc/agg084.

Abstract

AIMS

To investigate the onset and outcome of alcohol dependence in subjects with childhood attention deficit/hyperactivity disorder (ADHD) in a Turkish sample.

METHODS

Among patients being treated for alcohol dependence, 15 had a history of childhood ADHD [ADHD (+)] and 45 did not [ADHD (-)]. ADHD history was assessed according to DSM-IV criteria by a child and adolescent psychiatrist who interviewed the subjects and their close relatives. Severity of dependence was measured by the Michigan Alcoholism Screening Test. Subjects were followed up for 1 year for the assessment of relapse.

RESULTS

The age of onset for alcohol drinking, alcohol abuse and alcohol dependence were significantly lower in the ADHD (+) group than in the ADHD (-) group. Comorbid substance use was more prevalent in the ADHD (+) group. The study found no significant difference in the severity of alcohol dependence between ADHD (+) and ADHD (-) groups. During follow-up, 80% of the ADHD (+) subjects relapsed, compared with 55.6% in the ADHD (-) group. Relapse occurred on average 2.74 months earlier in the ADHD (+) group than in the ADHD (-) group.

CONCLUSIONS

As found in other countries, alcohol dependence in Turkish subjects with childhood ADHD starts early and is relatively resistant to treatment. Early diagnosis and treatment of ADHD might help prevent alcohol- and substance-related disorders.

摘要

目的

在一个土耳其样本中,调查患有儿童注意力缺陷多动障碍(ADHD)的受试者酒精依赖的发病情况及转归。

方法

在接受酒精依赖治疗的患者中,15例有儿童ADHD病史[ADHD(+)],45例无儿童ADHD病史[ADHD(-)]。儿童和青少年精神科医生根据《精神疾病诊断与统计手册》第四版(DSM-IV)标准,通过对受试者及其近亲进行访谈来评估ADHD病史。使用密歇根酒精ism筛查测试来衡量依赖的严重程度。对受试者进行为期1年的随访以评估复发情况。

结果

ADHD(+)组开始饮酒、酒精滥用和酒精依赖的年龄显著低于ADHD(-)组。共病物质使用在ADHD(+)组中更为普遍。研究发现ADHD(+)组和ADHD(-)组在酒精依赖严重程度上无显著差异。在随访期间,ADHD(+)组80%的受试者复发,而ADHD(-)组为55.6%。ADHD(+)组复发平均比ADHD(-)组早2.74个月。

结论

正如在其他国家所发现的,土耳其患有儿童ADHD的受试者酒精依赖发病早且相对难治。ADHD的早期诊断和治疗可能有助于预防酒精和物质相关障碍。

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