Ercan Eyüp Sabri, Coşkunol Hakan, Varan Azmi, Toksöz Kaan
Department of Child Psychiatry, Ege University, School of Medicine, Bornova, Izmir, Turkey.
Alcohol Alcohol. 2003 Jul-Aug;38(4):352-6. doi: 10.1093/alcalc/agg084.
To investigate the onset and outcome of alcohol dependence in subjects with childhood attention deficit/hyperactivity disorder (ADHD) in a Turkish sample.
Among patients being treated for alcohol dependence, 15 had a history of childhood ADHD [ADHD (+)] and 45 did not [ADHD (-)]. ADHD history was assessed according to DSM-IV criteria by a child and adolescent psychiatrist who interviewed the subjects and their close relatives. Severity of dependence was measured by the Michigan Alcoholism Screening Test. Subjects were followed up for 1 year for the assessment of relapse.
The age of onset for alcohol drinking, alcohol abuse and alcohol dependence were significantly lower in the ADHD (+) group than in the ADHD (-) group. Comorbid substance use was more prevalent in the ADHD (+) group. The study found no significant difference in the severity of alcohol dependence between ADHD (+) and ADHD (-) groups. During follow-up, 80% of the ADHD (+) subjects relapsed, compared with 55.6% in the ADHD (-) group. Relapse occurred on average 2.74 months earlier in the ADHD (+) group than in the ADHD (-) group.
As found in other countries, alcohol dependence in Turkish subjects with childhood ADHD starts early and is relatively resistant to treatment. Early diagnosis and treatment of ADHD might help prevent alcohol- and substance-related disorders.
在一个土耳其样本中,调查患有儿童注意力缺陷多动障碍(ADHD)的受试者酒精依赖的发病情况及转归。
在接受酒精依赖治疗的患者中,15例有儿童ADHD病史[ADHD(+)],45例无儿童ADHD病史[ADHD(-)]。儿童和青少年精神科医生根据《精神疾病诊断与统计手册》第四版(DSM-IV)标准,通过对受试者及其近亲进行访谈来评估ADHD病史。使用密歇根酒精ism筛查测试来衡量依赖的严重程度。对受试者进行为期1年的随访以评估复发情况。
ADHD(+)组开始饮酒、酒精滥用和酒精依赖的年龄显著低于ADHD(-)组。共病物质使用在ADHD(+)组中更为普遍。研究发现ADHD(+)组和ADHD(-)组在酒精依赖严重程度上无显著差异。在随访期间,ADHD(+)组80%的受试者复发,而ADHD(-)组为55.6%。ADHD(+)组复发平均比ADHD(-)组早2.74个月。
正如在其他国家所发现的,土耳其患有儿童ADHD的受试者酒精依赖发病早且相对难治。ADHD的早期诊断和治疗可能有助于预防酒精和物质相关障碍。