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[腹主动脉瘤筛查以合理成本挽救生命]

[Screening for abdominal aortic aneurysm saves lives at a reasonable cost].

作者信息

Swedenborg Jesper, Björck Martin, Wanhainen Anders, Bergqvist David

机构信息

Kärlkirurgiska kliniken, Karolinska sjukhuset, Stockholm.

出版信息

Lakartidningen. 2003 May 22;100(21):1886-91.

Abstract

Ruptured abdominal aortic aneurysms (AAA) cause 600 deaths per year in Sweden. As most patients are without symptoms prior to rupture, and about half the patients with a ruptured AAA die before arrival to hospital, the only way to reduce mortality substantially would be by screening and prophylactic treatment. The article reviews experience of screening for AAA from other European countries, data from the Swedish vascular registry (Swedvasc) and from the official registry of the causes of death in Sweden. With these data as input, a theoretical model of inviting all 65-year-old men in Sweden to take part in a screening programme for AAA is created. When the programme is fully developed after ten years, assuming an attendance rate of 75%, mortality in AAA would decrease from 630 to 346 per year. The total cost would increase from 154 to 161 million SEK (9 SEK = 1 Euro). The reason for the relatively minor increase in cost is explained by the fact that expensive emergency operations for ruptured AAA decrease by 50%. The cost per life saved would be 3,000-4,000 SEK. In conclusion, available data suggest that screening for AAA in Sweden would save many lives at a low cost.

摘要

在瑞典,腹主动脉瘤破裂每年导致600人死亡。由于大多数患者在破裂前没有症状,且约一半腹主动脉瘤破裂患者在抵达医院前死亡,大幅降低死亡率的唯一方法是进行筛查和预防性治疗。本文回顾了其他欧洲国家腹主动脉瘤筛查的经验、瑞典血管登记处(Swedvasc)的数据以及瑞典官方死亡原因登记处的数据。以这些数据为输入,创建了一个邀请瑞典所有65岁男性参加腹主动脉瘤筛查项目的理论模型。假设参与率为75%,十年后该项目全面开展时,腹主动脉瘤的死亡率将从每年630例降至346例。总成本将从1.54亿瑞典克朗增加到1.61亿瑞典克朗(9瑞典克朗 = 1欧元)。成本增加相对较小的原因是腹主动脉瘤破裂的昂贵急诊手术减少了50%。挽救每条生命的成本为3000 - 4000瑞典克朗。总之,现有数据表明,在瑞典进行腹主动脉瘤筛查将以低成本挽救许多生命。

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