Hosoi Satoshi, Mochizuki Teruhito, Miyagawa Masao, Shen Yun, Murase Kenya, Ikezoe Junpei
Department of Radiology, Ehime University School of Medicine Onsen-gun, Japan.
Radiat Med. 2003 Mar-Apr;21(2):62-7.
Multi-detector row CT (MDCT) is a new noninvasive modality for coronary artery imaging. Using the same MDCT data obtained for coronary artery assessment, left ventricular (LV) volumes such as end-diastolic (ED) and end-systolic (ES) volumes (EDV and ESV, respectively) and ejection fraction (EF) can potentially be assessed when ED and ES datasets are extracted. The purpose of this study was to evaluate the feasibility of MDCT in the assessment of LV volumes.
Using a pulsating heart phantom (EDV = 143 ml, ESV = 107 ml, stroke volume = 36 ml, EF = 25%) and MDCT, EDV and ESV were measured and EF was calculated. Clinical materials consisted of 11 consecutive human subjects who underwent MDCT. MDCT data were acquired during a single breathhold, using an intravenous injection of contrast medium. Left ventriculography (LVG) was performed in all patients as a gold standard. LV-EF was calculated by measuring ESV and EDV in all patients.
In the phantom study, LV volumes were: EDV = 137 ml, ESV = 101 ml, stroke volume = 36 ml, and EF = 26%. Close correlations were observed between MDCT values and LVG values (EDV: r = 0.95, ESV: r = 0.98, EF: r = 0.93, p < 0.001).
MDCT was useful for th e assessment of LV volumes and EF in various patients with CVD.
多排探测器CT（MDCT）是一种用于冠状动脉成像的新型无创检查方法。利用为评估冠状动脉而获取的相同MDCT数据，当提取舒张末期（ED）和收缩末期（ES）数据集时，有可能评估左心室（LV）容积，如舒张末期容积（EDV）和收缩末期容积（分别为ESV）以及射血分数（EF）。本研究的目的是评估MDCT在评估LV容积方面的可行性。
使用脉动心脏模型（EDV = 143 ml，ESV = 107 ml，每搏输出量 = 36 ml，EF = 25%）和MDCT，测量EDV和ESV并计算EF。临床资料包括11例连续接受MDCT检查的患者。通过静脉注射造影剂，在单次屏气期间采集MDCT数据。所有患者均进行左心室造影（LVG）作为金标准。通过测量所有患者的ESV和EDV计算左心室EF。
在模型研究中，LV容积为：EDV = 137 ml，ESV = 101 ml，每搏输出量 = 36 ml，EF = 26%。观察到MDCT值与LVG值之间具有密切相关性（EDV：r = 0.95，ESV：r = 0.98，EF：r = 0.93，p < 0.001）。
MDCT有助于评估各种心血管疾病（CVD）患者的LV容积和EF。
