Matsui Hikoro, Yasukochi Satoshi, Haseyama Keiji, Kaneko Sachie, Satomi Gengi
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100, Toyoshina, Toyoshina-machi, Minamiazumi-gun, Nagano, 399-8288, Japan.
Pediatr Cardiol. 2007 Jul-Aug;28(4):267-71. doi: 10.1007/s00246-006-1282-7.
Multidetector-row computed tomography (MDCT) of the heart is a new diagnostic approach for the quantitative evaluation of the coronary artery in adults. However, in children, the quantitative analysis of each cardiac chamber has not been established. We attempt to clarify the feasibility and validation of ECG-gated MDCT as a quantitative diagnostic tool to assess the right and left ventricular volume in children. The study consisted of 16 patients who had definite right and left ventricle. After obtaining multislice images by MDCT, we measured the end diastolic volume of both the right and the left ventricle by direct calculation of the region of interest and calculation from the projected image of three-dimensional reconstruction by traditional formulas. The correlation between the two calculations for both ventricles is excellent (r=0.99 for LV and 0.94 for RV, respectively). The correlations for ventricular volume between calculation of catheterization and calculation of MDCT is also good (r=0.99 for LV 0.99 for RV, respectively). Volume measurement by ECG-gated MDCT of the right and left ventricles is well correlated with that by catheterization in children and can reduce the necessity for cardiac catheterization.
心脏多排螺旋计算机断层扫描（MDCT）是一种用于定量评估成人冠状动脉的新诊断方法。然而，在儿童中，尚未建立对每个心腔的定量分析方法。我们试图阐明心电图门控MDCT作为评估儿童右心室和左心室容积的定量诊断工具的可行性和有效性。该研究包括16例有明确右心室和左心室的患者。通过MDCT获得多层图像后，我们通过直接计算感兴趣区域以及使用传统公式从三维重建的投影图像进行计算，来测量右心室和左心室的舒张末期容积。两个心室的两种计算方法之间的相关性非常好（左心室r = 0.99，右心室r = 0.94）。导管插入术计算与MDCT计算之间的心室容积相关性也很好（左心室r = 0.99，右心室r = 0.99）。儿童经心电图门控MDCT测量的右心室和左心室容积与导管插入术测量的结果具有良好的相关性，并且可以减少心脏导管插入术的必要性。
