Palma Paulo César Rodrigues, Vidal Benedicto, Riccetto Cássio Luís Zanettini, Herrmann Viviane, Dambros Míriam, Thiel Marcelo, Netto Nelson Rodrigues
Department of Urology, Faculty of Medical Sciences, State University of Campinas, UNICAMP, Campinas, São Paulo, Brazil.
J Endourol. 2003 May;17(4):255-9. doi: 10.1089/089277903765444410.
To assess whether the use of collagens with lipografts improves graft survival.
Thirty isogenic New Zealand rabbits were injected in the auricular area with either autologous fat alone or autologous fat associated with collagen. The animals were evaluated at 7, 30, and 90 days by histologic and morphometric methods together with measurements of the graft area and the number of adipocytes.
Addition of collagen to the lipoinjection reduced the local inflammatory reaction and improved the graft's survival; e.g., for stress urinary incontinence.
These results suggest that it is possible to increase the survival rate of the lipografts and improve their clinical applicability.
评估胶原蛋白与脂肪移植联合使用是否能提高移植物存活率。
30只同基因新西兰兔在耳部区域分别注射单纯自体脂肪或与胶原蛋白联合的自体脂肪。在第7天、30天和90天通过组织学和形态计量学方法以及测量移植物面积和脂肪细胞数量对动物进行评估。
在脂肪注射中添加胶原蛋白可减轻局部炎症反应并提高移植物存活率；例如，对于压力性尿失禁。
这些结果表明，提高脂肪移植物的存活率并改善其临床适用性是可能的。
