• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

抑制型和非抑制型婴儿“长大成人”:成年人杏仁核对新奇事物的反应。

Inhibited and uninhibited infants "grown up": adult amygdalar response to novelty.

作者信息

Schwartz Carl E, Wright Christopher I, Shin Lisa M, Kagan Jerome, Rauch Scott L

机构信息

Developmental Psychopathology Research Group, Department of Psychiatry, Massachusetts General Hospital (MGH), Harvard Medical School, 13th Street, Building 149, CNY-9, Charlestown, MA 02129, USA.

出版信息

Science. 2003 Jun 20;300(5627):1952-3. doi: 10.1126/science.1083703.

DOI:10.1126/science.1083703
PMID:12817151
Abstract

Infants with an inhibited temperament tend to develop into children who avoid people, objects, and situations that are novel or unfamiliar, whereas uninhibited children spontaneously approach novel persons, objects, and situations. Behavioral and physiological features of these two temperamental categories are moderately stable from infancy into early adolescence and have been hypothesized to be due, in part, to variation in amygdalar responses to novelty. We found that adults who had been categorized in the second year of life as inhibited, compared with those previously categorized as uninhibited, showed greater functional MRI signal response within the amygdala to novel versus familiar faces.

摘要

气质内向的婴儿往往会成长为回避新奇或陌生的人和事物及情境的儿童,而气质外向的儿童则会自发地接近新奇的人和事物及情境。这两种气质类型的行为和生理特征从婴儿期到青春期早期都具有一定程度的稳定性,据推测,部分原因是杏仁核对新奇事物的反应存在差异。我们发现,在生命第二年被归类为气质内向的成年人,与之前被归类为气质外向的成年人相比,杏仁核内对新奇面孔与熟悉面孔的功能性磁共振成像信号反应更强。

相似文献

1
Inhibited and uninhibited infants "grown up": adult amygdalar response to novelty.抑制型和非抑制型婴儿“长大成人”:成年人杏仁核对新奇事物的反应。
Science. 2003 Jun 20;300(5627):1952-3. doi: 10.1126/science.1083703.
2
Behavioral and physiological antecedents of inhibited and uninhibited behavior.抑制型和非抑制型行为的行为学及生理学先兆
Child Dev. 1996 Apr;67(2):523-40.
3
Differential amygdalar response to novel versus newly familiar neutral faces: a functional MRI probe developed for studying inhibited temperament.杏仁核对新奇与新熟悉的中性面孔的差异反应:一种为研究抑制性气质而开发的功能磁共振成像探针。
Biol Psychiatry. 2003 May 15;53(10):854-62. doi: 10.1016/s0006-3223(02)01906-6.
4
Temperament and the development of inhibited approach.气质与抑制性趋近行为的发展
Child Dev. 1988 Oct;59(5):1241-50.
5
Physical and physiological correlates of behavioral inhibition.行为抑制的身体和生理关联
Dev Psychobiol. 1989 Dec;22(8):753-70. doi: 10.1002/dev.420220802.
6
fMRI activation of the fusiform gyrus and amygdala to cartoon characters but not to faces in a boy with autism.一名患有自闭症男孩的功能性磁共振成像显示,梭状回和杏仁核被卡通人物激活,而对面孔无反应。
Neuropsychologia. 2005;43(3):373-85. doi: 10.1016/j.neuropsychologia.2004.06.015.
7
Amygdala temporal dynamics: temperamental differences in the timing of amygdala response to familiar and novel faces.杏仁核的时间动态:杏仁核对熟悉和陌生面孔反应时间的气质差异。
BMC Neurosci. 2009 Dec 10;10:145. doi: 10.1186/1471-2202-10-145.
8
Sustained amygdala response to both novel and newly familiar faces characterizes inhibited temperament.杏仁核对新的和新熟悉的面孔的持续反应是抑制气质的特征。
Soc Cogn Affect Neurosci. 2011 Oct;6(5):621-9. doi: 10.1093/scan/nsq073. Epub 2010 Jul 26.
9
Expectation and temperament moderate amygdala and dorsal anterior cingulate cortex responses to fear faces.期望和气质调节杏仁核和背侧前扣带回皮层对恐惧面孔的反应。
Cogn Affect Behav Neurosci. 2011 Mar;11(1):13-21. doi: 10.3758/s13415-010-0007-9.
10
Novel fearful faces activate the amygdala in healthy young and elderly adults.新颖的恐惧面孔会激活健康年轻人和老年人的杏仁核。
Neurobiol Aging. 2006 Feb;27(2):361-74. doi: 10.1016/j.neurobiolaging.2005.01.014. Epub 2005 Apr 13.

引用本文的文献

1
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis.儿童抑制性气质的脑结构关联:一项ENIGMA-焦虑症大型分析。
J Am Acad Child Adolesc Psychiatry. 2025 Jul 4. doi: 10.1016/j.jaac.2025.06.026.
2
Disentangling the role of different resting-state neural markers of adolescent behavioral inhibition and social anxiety.厘清青少年行为抑制和社交焦虑的不同静息态神经标志物的作用。
Dev Cogn Neurosci. 2025 Apr 24;73:101560. doi: 10.1016/j.dcn.2025.101560.
3
Applying evidence-based cross-disciplinary concepts helps to explain the heterogeneity in pain, function, and biological measures in individuals with knee pain with/at risk of osteoarthritis.
应用基于证据的跨学科概念有助于解释患有骨关节炎/有骨关节炎风险的膝关节疼痛患者在疼痛、功能和生物学指标方面的异质性。
Pain Rep. 2024 Dec 24;10(1):e1225. doi: 10.1097/PR9.0000000000001225. eCollection 2025 Feb.
4
Revisiting Jerome Kagan and his research legacy: An introduction to a special issue of Developmental Psychology.重新审视杰罗姆·卡根及其研究遗产:发展心理学特刊引言。
Dev Psychol. 2024 Nov;60(11):1949-1957. doi: 10.1037/dev0001885.
5
Respiratory Sinus Arrhythmia, Effortful Control, and Child Social Anxiety Symptoms.呼吸窦性心律失常、努力控制与儿童社交焦虑症状。
Res Child Adolesc Psychopathol. 2024 Sep;52(9):1441-1453. doi: 10.1007/s10802-024-01202-z. Epub 2024 Apr 26.
6
Categorical and latent profile approaches to temperamental infant reactivity and early trajectories of socioemotional adjustment.气质婴儿反应性的类别和潜在剖面方法及其社会情感调节的早期轨迹。
Dev Psychol. 2024 Nov;60(11):2071-2083. doi: 10.1037/dev0001679. Epub 2024 Jan 8.
7
Annual Research Review: Developmental pathways linking early behavioral inhibition to later anxiety.年度研究综述:早期行为抑制与后期焦虑之间的发展途径。
J Child Psychol Psychiatry. 2023 Apr;64(4):537-561. doi: 10.1111/jcpp.13702. Epub 2022 Sep 19.
8
Proceedings of the 2021 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group.2021 年胎儿酒精谱系障碍研究组年会会议记录。
Alcohol. 2022 Aug;102:23-33. doi: 10.1016/j.alcohol.2022.04.006. Epub 2022 May 18.
9
The endocannabinoid system in social anxiety disorder: from pathophysiology to novel therapeutics.社交焦虑障碍中的内源性大麻素系统:从病理生理学到新疗法。
Braz J Psychiatry. 2022 Jan-Feb;44(1):81-93. doi: 10.1590/1516-4446-2021-1926.
10
Neural Responses to Social Reward Predict Depressive Symptoms in Adolescent Girls During the COVID-19 Pandemic.社交奖励引发的神经反应可预测新冠疫情期间青春期女孩的抑郁症状。
J Pediatr Psychol. 2021 Aug 19;46(8):915-926. doi: 10.1093/jpepsy/jsab037.