Conner Kenneth R, Li Yue, Meldrum Sean, Duberstein Paul R, Conwell Y
Department of Psychiatry, University of Rochester Medical Center, Rochester, New York 14642, USA.
J Stud Alcohol. 2003 May;64(3):402-8. doi: 10.15288/jsa.2003.64.402.
The associations of suicidal ideation with both the intensity (drinks per drinking day) and frequency of alcohol consumption were examined in a longitudinal study of treated alcoholics.
The data are from alcohol dependent subjects (1,187 men and 374 women) enrolled in Project MATCH, a multisite clinical trial of psychosocial treatments of alcoholism. Multivariate analyses for correlated data using generalized estimating equation approaches were performed to examine correlates of suicidal ideation at study entry and at 3-, 9- and 15-month follow-up. Analyses were stratified by gender and controlled statistically for depression and alcoholism severity.
Suicidal ideation was common among women (15.5%) and men (9.9%) entering treatment, and at least 3.6% of women and 4.2% of men reported suicidal ideation at each follow-up. There were gender patterns in suicidal ideation. In women, intensity was associated with suicidal ideation, but even nonintense drinking became associated with suicidal ideation with more frequent drinking (intensity-frequency interaction). In men, intensity was also associated with suicidal ideation, whereas frequency was unrelated. Antisocial personality disorder in men but not in women, and depression in both groups, were also linked to suicidal ideation.
Suicidal ideation is prevalent among treated alcoholics. Drinking is strongly associated with suicidal ideation and in women even light drinking, if it occurs regularly, is associated with suicidal ideation, with implications for suicide risk-recognition and intervention.
在一项针对接受治疗的酗酒者的纵向研究中，考察自杀意念与饮酒强度（每日饮酒量）及饮酒频率之间的关联。
数据来自参与“匹配项目”的酒精依赖受试者（1187名男性和374名女性），该项目是一项关于酗酒心理社会治疗的多中心临床试验。采用广义估计方程方法对相关数据进行多变量分析，以考察研究开始时以及3个月、9个月和15个月随访时自杀意念的相关因素。分析按性别分层，并对抑郁和酗酒严重程度进行统计学控制。
进入治疗的女性（15.5%）和男性（9.9%）中，自杀意念很常见，每次随访时至少有3.6%的女性和4.2%的男性报告有自杀意念。自杀意念存在性别模式。在女性中，饮酒强度与自杀意念有关，但即使饮酒强度不高，随着饮酒频率增加也会与自杀意念相关（强度-频率交互作用）。在男性中，饮酒强度也与自杀意念有关，而饮酒频率则无关。男性而非女性的反社会人格障碍以及两组中的抑郁也与自杀意念有关。
自杀意念在接受治疗的酗酒者中很普遍。饮酒与自杀意念密切相关，在女性中，即使是少量饮酒，如果经常发生，也与自杀意念有关，这对自杀风险识别和干预具有启示意义。
