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3729名酒精依赖男性和女性的自杀意念、计划以及意外和蓄意自杀未遂的转变情况及其相关因素。

Transitions to, and correlates of, suicidal ideation, plans, and unplanned and planned suicide attempts among 3,729 men and women with alcohol dependence.

作者信息

Conner Kenneth R, Hesselbrock Victor M, Meldrum Sean C, Schuckit Marc A, Bucholz Kathleen K, Gamble Stephanie A, Wines James D, Kramer John

机构信息

Center for the Study and Prevention of Suicide and the Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, New York 14620, USA.

出版信息

J Stud Alcohol Drugs. 2007 Sep;68(5):654-62. doi: 10.15288/jsad.2007.68.654.

Abstract

OBJECTIVE

Using a heuristic model of suicidal ideation and behavior, the two objectives were to identify correlates of (1) unique suicide-related outcomes (ideation, planning, planned attempt, unplanned attempt) and (2) specific transitions from one suicide-related category to the next.

METHOD

Analyses were conducted with data from the Collaborative Study on the Genetics of Alcoholism (COGA), a six-site family pedigree study of individuals in treatment for alcoholism, their relatives, and control families. There were 3,729 subjects in the analysis; all were age 18 years or older with a diagnosis of current alcohol dependence according to the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised. Lifetime suicidal ideation, planning, and attempts were analyzed retrospectively. Correlates of each lifetime transition were analyzed using a series of multivariate logistic regressions. Multivariate multinomial regression analysis was used to examine correlates of each lifetime outcome.

RESULTS

Female gender is uniquely associated with transitions to unplanned and planned attempts. Independent depression and substance-induced depression are associated with transitions to ideation and planning, whereas alcohol-related aggression is correlated with transitions to unplanned attempts. Analyses of suicide-related outcomes show that women are at higher risk for unplanned and planned attempts. Substance use and impairment are related to suicidal plans and attempts but not ideation. Independent and substance-induced depressions are associated with each suicide-related outcome, whereas alcohol-related aggression is uniquely related to unplanned attempts.

CONCLUSIONS

Data underscore the heterogeneity of suicidal ideation and behavior among alcoholics and indicate the need to make clear distinctions between types of suicidal ideation and behavior in research and prevention efforts.

摘要

目的

运用自杀意念与行为的启发式模型,两个目标是确定(1)独特的自杀相关结局(意念、计划、计划实施的企图、非计划实施的企图)的相关因素,以及(2)从一个自杀相关类别到下一个类别的特定转变。

方法

分析采用了来自酒精中毒遗传学合作研究(COGA)的数据,这是一项针对接受酒精中毒治疗的个体、其亲属及对照家庭的六地点家系研究。分析中有3729名受试者;所有受试者年龄均在18岁及以上,根据《精神障碍诊断与统计手册》第三版修订本,诊断为当前酒精依赖。对终生自杀意念、计划和企图进行回顾性分析。使用一系列多变量逻辑回归分析每个终生转变的相关因素。多变量多项回归分析用于检验每个终生结局的相关因素。

结果

女性性别与向非计划和计划实施的企图的转变独特相关。独立的抑郁症和物质所致抑郁症与向意念和计划的转变相关,而与酒精相关的攻击行为与向非计划实施的企图的转变相关。对自杀相关结局的分析表明,女性在非计划和计划实施的企图方面风险更高。物质使用和损害与自杀计划及企图有关,但与意念无关。独立的和物质所致的抑郁症与每个自杀相关结局相关,而与酒精相关的攻击行为则与非计划实施的企图独特相关。

结论

数据强调了酗酒者自杀意念和行为的异质性,并表明在研究和预防工作中需要明确区分自杀意念和行为的类型。

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