Phillips Nicole, Priestley Mark, Denniss A Robert, Uther John B
Department of Anesthesia, Westmead Hospital, Australia.
Anesth Analg. 2003 Jul;97(1):264-7, table of contents. doi: 10.1213/01.ane.0000067410.32384.3a.
In this case report, we describe the postoperative occurrence of electrocardiogram changes suggestive for the Brugada syndrome in a patient receiving a continuous epidural bupivacaine infusion. After withdrawal of bupivacaine, the electrocardiogram changes were reversible. The patient's history was unremarkable except for an incomplete right bundle branch block. We conclude that local anesthetics, particularly bupivacaine, have the potential to induce serious arrhythmias in patients with Brugada syndrome.
在本病例报告中，我们描述了一名接受连续硬膜外布比卡因输注的患者术后出现提示Brugada综合征的心电图变化。停用布比卡因后，心电图变化是可逆的。除不完全性右束支传导阻滞外，患者病史无异常。我们得出结论，局部麻醉药，尤其是布比卡因，有可能在Brugada综合征患者中诱发严重心律失常。
