Coindre J M
Department of Pathology, Institut Bergonié and University Victor Segalen Bordeaux 2, 229 Cours de l'Argonne, 33076 Bordeaux cedex, France.
Histopathology. 2003 Jul;43(1):1-16. doi: 10.1046/j.1365-2559.2003.01639.x.
Immunohistochemistry is particularly important in the field of soft tissue tumours because of their variety and the frequent difficulty of diagnosis. The first part of this paper discusses useful or new antibodies, together with others that are no longer of use. The second part is devoted to the role of immunohistochemistry in the diagnosis of soft tissue tumours: identification of some rare or atypical benign lesions, identification of non-mesenchymal malignant tumours, and classification of sarcomas. The respective roles of immunohistochemistry and molecular biology are underlined.
免疫组织化学在软组织肿瘤领域尤为重要，因为其种类繁多且诊断常常困难。本文第一部分讨论了有用的或新的抗体，以及其他不再有用的抗体。第二部分致力于免疫组织化学在软组织肿瘤诊断中的作用：识别一些罕见或非典型的良性病变、识别非间叶性恶性肿瘤以及肉瘤的分类。强调了免疫组织化学和分子生物学各自的作用。
