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巨大原发性阴道肉瘤:一例报告及文献综述。

A giant primary vaginal sarcoma: A report case and literature review.

作者信息

Moukhlissi Mohamed, Ben Sghier Ahmed, Serji Badr, El Harroudi Tijani, Bennani Amal, Dahbi Zineb, Berhilli Soufinae, Mezouar Loubna

机构信息

Radiotherapy Department, University Mohamed VI Hospital, Mohamed First University Oujda, Oujda, Morocco.

Surgery Department, University Mohamed VI Hospital, Mohamed First University Oujda, Oujda, Morocco.

出版信息

Radiol Case Rep. 2023 Mar 7;18(5):1872-1876. doi: 10.1016/j.radcr.2023.02.024. eCollection 2023 May.

DOI:10.1016/j.radcr.2023.02.024
PMID:36936806
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10017309/
Abstract

Primary vaginal sarcoma is a rare disease entity, reported in less than 3% of cases of vaginal cancers. We report the observation of a patient treated at the regional oncology center of Oujda in Morocco who is presented with a non-metastatic primary vaginal leiomyosarcoma of 20 cm. The treatment consisted of neoadjuvant chemotherapy, followed by hemostatic surgery with tumor resection limits, reinforced by radiotherapy and then a surgical resection with a tumor resection taking away the infiltrated part of the anterior face of the lower rectum and the realization of a left iliac colostomy whose resected tumor part limits were healthy. At present, the patient is 4 years of follow-up without locoregional or distant recurrence.

摘要

原发性阴道肉瘤是一种罕见的疾病实体,在阴道癌病例中报告的比例不到3%。我们报告了一名在摩洛哥乌季达地区肿瘤中心接受治疗的患者,该患者患有20厘米的非转移性原发性阴道平滑肌肉瘤。治疗包括新辅助化疗,随后进行止血手术并确定肿瘤切除范围,辅以放疗,然后进行手术切除,切除肿瘤时一并切除下直肠前壁的浸润部分,并实施左髂结肠造口术,切除的肿瘤部分边缘均为健康组织。目前,该患者已随访4年,无局部或远处复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/bff47e57399d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/f6eea055840b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/c6ad1a5a3589/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/bff47e57399d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/f6eea055840b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/c6ad1a5a3589/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/10017309/bff47e57399d/gr3.jpg

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引用本文的文献

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Primary vaginal leiomyosarcoma: A case report emphasizing multidisciplinary care of a rare entity.原发性阴道平滑肌肉瘤:一例强调对罕见疾病进行多学科治疗的病例报告。
Radiol Case Rep. 2025 Jun 18;20(9):4444-4448. doi: 10.1016/j.radcr.2025.05.024. eCollection 2025 Sep.

本文引用的文献

1
When an Unexpected Diagnosis Occurs: a Vaginal Premenopausal Sarcoma.当出现意外诊断结果时:一例绝经前阴道肉瘤
Rev Bras Ginecol Obstet. 2018 Jan;40(1):47-52. doi: 10.1055/s-0037-1615293. Epub 2018 Jan 16.
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Multimodality imaging of vaginal rhabdomyosarcoma.阴道横纹肌肉瘤的多模态成像
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Magnetic resonance imaging of the vagina: an overview for radiologists with emphasis on clinical decision making.阴道的磁共振成像:面向放射科医生的概述,重点在于临床决策制定
Radiol Bras. 2015 Jul-Aug;48(4):249-59. doi: 10.1590/0100-3984.2013.1726.
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Primary vaginal sarcoma: Experience of a regional cancer center in China.原发性阴道肉瘤:中国某区域癌症中心的经验
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Comparing mortality of vaginal sarcoma, squamous cell carcinoma, and adenocarcinoma in the surveillance, epidemiology, and end results database.比较监测、流行病学和最终结果数据库中阴道肉瘤、鳞状细胞癌和腺癌的死亡率。
Obstet Gynecol. 2015 Jun;125(6):1353-1361. doi: 10.1097/AOG.0000000000000861.
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[Fourth edition of WHO classification tumours of soft tissue].[世界卫生组织软组织肿瘤分类第四版]
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Int J Gynecol Cancer. 2014 Jan;24(1):156-64. doi: 10.1097/IGC.0000000000000011.
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Sarcoma of vulva, vagina and ovary.外阴、阴道和卵巢肉瘤。
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Leiomyosarcoma of the vagina: case report and literature review.阴道平滑肌肉瘤:病例报告及文献综述
Int J Gynecol Cancer. 2006 Mar-Apr;16(2):884-91. doi: 10.1111/j.1525-1438.2006.00487.x.
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Immunohistochemistry in the diagnosis of soft tissue tumours.免疫组织化学在软组织肿瘤诊断中的应用
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