Douglas Raymond S, Duncan Jacque, Brucker Allison, Prenner Jonathan L, Brucker Alexander J
Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19103, USA.
Retina. 2003 Jun;23(3):348-53. doi: 10.1097/00006982-200306000-00010.
To describe the natural history of a series of patients with a small foveal or juxtafoveal red lesion.
Retrospective chart review of 13 patients with a small foveal or juxtafoveal red spot. Long-term follow-up examination was obtained in seven patients.
Thirteen patients with a mean age of 34.6 years are reported. Initial visual complaints ranged from no complaints to mild blurring and central distortion of vision. None of the patients had a history of sun gazing or known macular disease. Eleven of the 13 patients had best-corrected visual acuities in the involved eye that were better than 20/30. The lesions were bilateral in five patients and unilateral in eight. When performed, optical coherence tomography and fluorescein angiography were unremarkable. Follow-up was obtained in seven patients (mean, 58 months), and visual acuity remained stable in all affected eyes. In all patients, the lesions remained stable without expansion or alteration of the foveal appearance over the course of follow-up.
This report identifies a foveal or juxtafoveal, irregular, apparently intraretinal, red lesion of unclear cause. Long-term follow-up of these patients has demonstrated stable visual acuity and lesion appearance.
描述一系列患有小黄斑或黄斑旁红色病变患者的自然病程。
对13例患有小黄斑或黄斑旁红色斑点的患者进行回顾性病历审查。7例患者进行了长期随访检查。
报告了13例平均年龄为34.6岁的患者。最初的视觉症状从无不适到轻度视力模糊和中心视力扭曲不等。所有患者均无凝视阳光或已知黄斑疾病史。13例患者中有11例患眼的最佳矫正视力优于20/30。病变在5例患者中为双侧，8例为单侧。进行光学相干断层扫描和荧光素血管造影时未见异常。7例患者（平均58个月）进行了随访，所有患眼的视力均保持稳定。在所有患者中，病变在随访过程中保持稳定，未出现扩大或黄斑外观改变。
本报告确定了一种病因不明的黄斑或黄斑旁、不规则、明显位于视网膜内的红色病变。对这些患者的长期随访显示视力和病变外观稳定。
