Arruda-Olson Adelaide M, Olson Lyle J, Nehra Ajay, Somers Virend K
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Herz. 2003 Jun;28(4):298-303. doi: 10.1007/s00059-003-2482-z.
There is increasing recognition of the high and rising prevalence of obstructive sleep apnea (OSA). It has been suggested that OSA may contribute to erectile dysfunction. This review will examine the evidence and potential mechanisms, including abnormalities of neural, endothelial and hormonal function, linking OSA to erectile dysfunction.
Available data suggest, but do not prove, a higher prevalence of erectile dysfunction in OSA. Certainly, the pathologic processes activated by OSA are also those that may predispose to impaired erectile function. Further well-designed and controlled studies are needed to show conclusively that any increased prevalence of erectile dysfunction in OSA is secondary to the OSA per se and not a consequence of the frequently associated comorbidities, such as obesity and vascular disease, that characterize this patient population.
阻塞性睡眠呼吸暂停（OSA）的高患病率及其不断上升的趋势正日益受到关注。有人提出，OSA可能导致勃起功能障碍。本综述将研究将OSA与勃起功能障碍联系起来的证据及潜在机制，包括神经、内皮和激素功能异常。
现有数据表明（但未证实），OSA患者勃起功能障碍的患病率较高。当然，OSA激活的病理过程也是那些可能导致勃起功能受损的过程。需要进一步设计良好且对照严格的研究，以确凿证明OSA患者中勃起功能障碍患病率的任何增加是继发于OSA本身，而非该患者群体常见合并症（如肥胖和血管疾病）的结果。
