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空肠弯曲菌感染的点源暴发——它们是否比我们想象的更常见,原因可能是什么?

Point source outbreaks of Campylobacter jejuni infection--are they more common than we think and what might cause them?

作者信息

Gillespie I A, O'Brien S J, Adak G K, Tam C C, Frost J A, Bolton F J, Tompkins D S

机构信息

PHLS Communicable Disease Surveillance Centre, 61 Colindale Avenue, London.

出版信息

Epidemiol Infect. 2003 Jun;130(3):367-75.

Abstract

Despite being the commonest bacterial cause of infectious intestinal disease (IID) in England and Wales, outbreaks of campylobacter infection are rarely reported. However, data from the Campylobacter Sentinel Surveillance Scheme suggested that outbreaks might be more common than was previously suspected, since a high proportion of cases reported other illness in the home or in the community at the same time as their illness. To identify factors that might lead to these apparent outbreaks, the exposures of cases of Campylobacter jejuni infection reporting other illness, either in the home or the community, were compared with those for cases not reporting other illness using case-case methodology. Illness in the home was associated with consuming organic meats in the winter, having contact with a pet suffering from diarrhoea or visiting a farm in the 2 weeks before the onset of symptoms. Illness in the community was associated with the consumption of foods in restaurants or drinking unpasteurized milk. Prevention of campylobacter infection requires that better methods of outbreak detection and investigation are developed, which in turn should lead to a better understanding of risk factors.

摘要

尽管弯曲杆菌感染是英格兰和威尔士感染性肠道疾病(IID)最常见的细菌病因,但弯曲杆菌感染的暴发却很少被报道。然而,弯曲杆菌哨点监测计划的数据表明,暴发可能比之前怀疑的更为常见,因为很大比例的病例在患病的同时还报告了家中或社区内的其他疾病。为了确定可能导致这些明显暴发的因素,采用病例对照方法,将报告家中或社区内其他疾病的空肠弯曲杆菌感染病例的暴露情况与未报告其他疾病的病例进行了比较。家中患病与冬季食用有机肉类、接触患有腹泻的宠物或在症状出现前两周内参观农场有关。社区患病与在餐馆食用食物或饮用未经巴氏消毒的牛奶有关。预防弯曲杆菌感染需要开发更好的暴发检测和调查方法,这反过来又应有助于更好地了解危险因素。

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