Peixinho P, Sabino T, Duarte C, Cruz T, Bragança N
Serviço de Medicina 2, Hospital de Curry Cabral, Lisboa.
Acta Med Port. 2003 Mar-Apr;16(2):97-9.
Aspergillosis, the most frequent of pulmonary mycosis, represents a group of varying pathogenesis diseases with the same etiological agent--Aspergillus. This fungus is a saprophyte of normal respiratory airways, but the disease occurs in immunocompromised hosts. There are several anatomo-clinical forms, but it is important to know that some could be fatal, being necessary an early diagnosis and therapy. The authors describe an Invasive Pulmonary Aspegillosis case, in a immunocompromised patient submitted to long term corticotherapy treatment. Was started with liposomal Amphotericin B, discontinued due to nephrotoxicity and substituted by Itraconazol, with clinical, laboratorial and radiologic favourable evolution, as it's proven by imagiological studies.
曲霉病是最常见的肺部真菌病，是一组病因相同（曲霉菌）但发病机制各异的疾病。这种真菌是正常呼吸道的腐生菌，但疾病发生在免疫功能低下的宿主中。有几种解剖学 - 临床类型，但重要的是要知道有些可能是致命的，因此早期诊断和治疗是必要的。作者描述了一例侵袭性肺曲霉病病例，患者为一名接受长期皮质激素治疗的免疫功能低下患者。最初使用脂质体两性霉素B治疗，因肾毒性而停药，改用伊曲康唑，经影像学研究证实，患者在临床、实验室和影像学方面均有良好转归。
