Taylor Susan, Armour Carol
Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia.
Pharmacoeconomics. 2003;21(10):721-35. doi: 10.2165/00019053-200321100-00004.
To assess consumer preference for two methods of induction of labour using stated preference discrete choice modelling. The methods of induction were artificial rupture of the membranes (ARM) plus oxytocin and dinoprostone (prostaglandin E(2)) vaginal gel, followed by oxytocin if necessary.
Consumer preference was measured in terms of willingness to pay for each of the attributes. These attributes were the method of administration, place of care, length of time from induction to delivery, need for epidural anaesthetic, type of delivery and cost. Levels were assigned to each of the attributes. Pregnant women attending a public hospital antenatal clinic were asked to read a description of the two methods and then to choose between them in 18 different scenarios in which the levels of the attributes were varied.
Women were willing to pay 11 Australian dollars for a 1% reduction in the chance of needing oxytocin as well as the gel and 55 Australian dollars for every 1 hour reduction in the length of time from induction to delivery. For a 1% reduction in the chance of needing an epidural anaesthetic or Caesarean section, women expressed a willingness to pay of 20 Australian dollars and 90 Australian dollars, respectively. All estimates were obtained in 1998 and expressed in Australian dollars (1 Australian dollar = 0.63 US dollars).
Women valued the less invasive method of administration of the gel and the associated greater freedom of movement during labour. However, they valued the shorter time from induction to delivery associated with ARM plus oxytocin more highly. A policy which allows women access to the gel for up to two doses would accommodate this consumer preference.
采用陈述偏好离散选择模型评估消费者对两种引产方法的偏好。引产方法为人工破膜（ARM）加催产素以及地诺前列酮（前列腺素E₂）阴道凝胶，必要时再使用催产素。
根据为每种属性支付的意愿来衡量消费者偏好。这些属性包括给药方法、护理地点、从引产到分娩的时长、是否需要硬膜外麻醉、分娩方式和费用。为每个属性设定了不同水平。要求在公立医院产前诊所就诊的孕妇阅读两种方法的描述，然后在18种不同情景中进行选择，这些情景中属性水平各不相同。
女性愿意为催产素及凝胶需求几率降低1%支付11澳元，为从引产到分娩时长每缩短1小时支付55澳元。对于硬膜外麻醉或剖宫产需求几率降低1%，女性分别表示愿意支付20澳元和90澳元。所有估值均于1998年获得，以澳元表示（1澳元 = 0.63美元）。
女性重视凝胶给药这种侵入性较小的方法以及分娩期间更大的活动自由度。然而，她们更看重与ARM加催产素相关的从引产到分娩的更短时间。允许女性使用凝胶最多两剂的政策将符合这种消费者偏好。
