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戒酒可逆转严重酒精性心肌病。

Severe alcoholic cardiomyopathy reversed with abstention from alcohol.

作者信息

Schwartz L, Sample K A, Wigle D E

出版信息

Am J Cardiol. 1975 Dec;36(7):963-6. doi: 10.1016/0002-9149(75)90090-9.

DOI:10.1016/0002-9149(75)90090-9
PMID:128286
Abstract

In a chronic alcoholic with a severe congestive cardiomyopathy the angiographic and hemodynamic evidence of left ventricular dysfunction was completely reversed after 1 year of abstinence. At the time of initial presentation two of the traditional hallmarks of a poor prognosis were present, namely, a long exposure to alcohol before the onset of symptoms and severe diffuse left ventricular dilation and hypokinesis (ejection fraction 14.9 percent). Yet, today, 18 months later he is asymptomatic, receiving no medications and has normal left ventricular function. A reexamination of prognostic factors in alcoholic cardiomyopathy may be indicated.

摘要

在一名患有严重充血性心肌病的慢性酒精中毒患者中,经过1年戒酒,左心室功能障碍的血管造影和血流动力学证据完全逆转。初次就诊时,存在两个预后不良的传统标志,即症状出现前长期饮酒以及严重的弥漫性左心室扩张和运动减弱(射血分数为14.9%)。然而,18个月后的今天,他没有症状,未服用任何药物,左心室功能正常。可能需要重新审视酒精性心肌病的预后因素。

相似文献

1
Severe alcoholic cardiomyopathy reversed with abstention from alcohol.戒酒可逆转严重酒精性心肌病。
Am J Cardiol. 1975 Dec;36(7):963-6. doi: 10.1016/0002-9149(75)90090-9.
2
[Course and prognosis of apparently primary congestive cardiomyopathies in chronic alcoholic patients].[慢性酒精性患者明显原发性充血性心肌病的病程及预后]
Ann Cardiol Angeiol (Paris). 1985 Oct;34(8):525-30.
3
Variable prognosis in congestive cardiomyopathy. Role of left ventricular function, alcoholism, and pulmonary thrombosis.
Jpn Heart J. 1980 Jul;21(4):451-63.
4
[Alcoholic Cardiomyopathy (author's transl)].
MMW Munch Med Wochenschr. 1976 Mar 19;118(12):355-60.
5
[Dilated cardiomyopathy with deep, completely reversible dysfunction of the left heart in alcoholic patients. Report of 2 cases].[酒精性心肌病患者左心深度、完全可逆性功能障碍。2例报告]
Arch Mal Coeur Vaiss. 1990 Nov;83(12):1843-7; discussion 1853.
6
Prediction of recovery after abstinence in alcoholic cardiomyopathy: role of hemodynamic and morphometric parameters.
Clin Cardiol. 1996 Jan;19(1):45-50. doi: 10.1002/clc.4960190109.
7
[The etiology, course and prognosis of dilated cardiomyopathy].[扩张型心肌病的病因、病程及预后]
Z Kardiol. 1982 Aug;71(8):497-508.
8
Differences of disease progression in congestive heart failure due to alcoholic as compared to idiopathic dilated cardiomyopathy.酒精性充血性心力衰竭与特发性扩张型心肌病在疾病进展方面的差异。
Eur Heart J. 1996 Feb;17(2):251-7. doi: 10.1093/oxfordjournals.eurheartj.a014842.
9
Electrocardiographic abnormalities in alcoholic cardiomyopathy. A study of 65 patients.酒精性心肌病的心电图异常。65例患者的研究。
Chest. 1975 Jul;68(1):24-7. doi: 10.1378/chest.68.1.24.
10
[Echocardiographic evaluation of cardiac involvement in patients with chronic alcoholism].
J Cardiogr. 1983 Sep;13(3):551-70.

引用本文的文献

1
Alcoholic cardiomyopathy: an update.酒精性心肌病:更新。
Eur Heart J. 2024 Jul 9;45(26):2294-2305. doi: 10.1093/eurheartj/ehae362.
2
Congestive heart failure arising from diastolic dysfunction in the presence of normal left-ventricular systolic function.在左心室收缩功能正常的情况下,由舒张功能障碍引起的充血性心力衰竭。
Tex Heart Inst J. 1999;26(1):34-41.
3
Ultrastructural morphometric study on the rat heart after chronic ethanol feeding.慢性乙醇喂养后大鼠心脏的超微结构形态计量学研究。
Virchows Arch A Pathol Anat Histol. 1980;389(1):59-77. doi: 10.1007/BF00428668.
4
Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.非氧化乙醇代谢:胆固醇酯酶催化脂肪酸乙酯的形成。
Proc Natl Acad Sci U S A. 1982 Jul;79(13):3954-7. doi: 10.1073/pnas.79.13.3954.
5
Reversibility of alcoholic cardiomyopathy.酒精性心肌病的可逆性。
Postgrad Med J. 1984 Feb;60(700):151-4. doi: 10.1136/pgmj.60.700.151.
6
The effect of abstinence on left ventricular performance in asymptomatic chronic alcoholics.
Cardiovasc Intervent Radiol. 1983;6(3):154-9. doi: 10.1007/BF02552768.
7
Mitochondrial dysfunction induced by fatty acid ethyl esters, myocardial metabolites of ethanol.脂肪酸乙酯(乙醇的心肌代谢产物)诱导的线粒体功能障碍。
J Clin Invest. 1983 Aug;72(2):724-31. doi: 10.1172/JCI111022.
8
Cardiac abnormalities in liver cirrhosis.肝硬化中的心脏异常。
West J Med. 1989 Nov;151(5):530-5.
9
Cardiovascular effects of alcohol.酒精对心血管的影响。
West J Med. 1989 Oct;151(4):430-9.
10
Abstention from alcohol in dilated cardiomyopathy: complete regression of the clinical disease but persistence of myocardial perfusion defects on exercise thallium-201 tomography.扩张型心肌病患者戒酒:临床疾病完全消退,但运动铊-201断层扫描显示心肌灌注缺损持续存在。
Eur J Nucl Med. 1990;17(5):279-81. doi: 10.1007/BF00812370.