Nicolás Torralba José Antonio, Tornero Ruiz Jesús, Bañón Pérez Vicente, Server Pastor Gerardo, López Cubillana Pedro, Pérez Albacete Mariano
Servicio de Urología, Hospital Universitario Virgen de la Arrixaca, Ctra. Madrid-Cartagena s/n 30120 El Palmar, Murcia, España.
Arch Esp Urol. 2003 May;56(4):355-8.
To confirm the relationship between hypertension and lower urinary tract symptoms (LUTS) in our environment, and to evaluate the association between hypertension and LUTS secondary to benign prostatic hypertrophy (BPH).
We prospectively studied during 3 months all male patients older than 50 years (163 patients) analysing previous medical history, IPSS, digital rectal examination, urine sediment, basic biochemical profile, PSA, uroflowmetry, and urinary tract ultrasound. Patients with neurological diseases, previous pelvic trauma, diabetes mellitus, suspicious digital rectal examination, abnormal PSA, or under treatment with alpha blockers, antidepressants, finasteride or antipsychotic drugs were excluded.
From a total of 163 patients 113 were classified as suffering clinical BPH (LUTS, prostate greater than 30 gm, and uroflowmetry < 15 ml/sec), and 75 as hypertensive. Among 75 hypertensive patients 31 presented IPSS greater than 7 (41.3%) in comparison to 20 out of 88 non hypertensive patients (22.7%), being the difference statistically significant.
Our study confirms what has been previously reported by other authors, that there is a statistically significant relationship between hypertension and LUTS secondary to BPH.
在我们的研究环境中确认高血压与下尿路症状（LUTS）之间的关系，并评估高血压与良性前列腺增生（BPH）继发的LUTS之间的关联。
我们对3个月内所有年龄超过50岁的男性患者（163例）进行了前瞻性研究，分析了既往病史、国际前列腺症状评分（IPSS）、直肠指检、尿沉渣、基本生化指标、前列腺特异性抗原（PSA）、尿流率测定和泌尿系统超声检查。排除患有神经系统疾病、既往有盆腔创伤、糖尿病、直肠指检可疑、PSA异常或正在接受α受体阻滞剂、抗抑郁药、非那雄胺或抗精神病药物治疗的患者。
在总共163例患者中，113例被归类为患有临床BPH（LUTS、前列腺大于30克且尿流率<15毫升/秒），75例为高血压患者。在75例高血压患者中，31例的IPSS大于7（41.3%），而88例非高血压患者中有20例（22.7%），差异具有统计学意义。
我们的研究证实了其他作者先前报道的内容，即高血压与BPH继发的LUTS之间存在统计学上的显著关系。
