Márquez Moreno Antonio Javier, Mañas Uxó Jorge, Amores Ramírez Francisco, Aguilar Cuevas Rafael, Ortega Jiménez María Victoria, Leiva Vera Carmen, Pérez Rodríguez Diego
Servicios de Radiodiagnóstico, Hospital Clínico Universitario, Málaga, España.
Arch Esp Urol. 2003 May;56(4):415-7.
To report a case of synchronic neoplasia--chromophobe renal cell carcinoma and low grade non Hodgkin lymphoma--in a 38-year-old male patient, because, although association of these two neoplasias is known, the fact of renal neoplasia being a chromophobe carcinoma is rarely referred to in medical bibliography (3 cases described after Med-Line search).
METHODS/RESULTS: The diagnostic study included ultrasound and CT scan in a patient presenting with in non specific abdominal symptoms and neck adenopathy; patient underwent left radical nephrectomy and excision of neck adenopathy. Histologic and immuno-histochemical studies revealed the coexistence of chromophobe type renal cell carcinoma and diffuse centrocytic lymphoma.
Column in the association between chromophobe histological type renal cell carcinoma and non Hodgkin lymphoma is very rare. Presence of these two tumors in the same patient may pose problems for clinical staging, prognostic predictions, and treatment. Then, due to the fact that it is not usual and that a local stage renal carcinoma presents with neck adenopathies, when they appear possible coexistence of these tumors should be suspected.
报告一例38岁男性患者同时发生的肿瘤——嫌色肾细胞癌和低级别非霍奇金淋巴瘤，因为尽管这两种肿瘤的关联已为人所知，但医学文献中很少提及肾肿瘤为嫌色癌的情况（经医学在线检索后仅描述了3例）。
方法/结果：对一名出现非特异性腹部症状和颈部淋巴结病的患者进行的诊断性检查包括超声和CT扫描；患者接受了左肾根治性切除术及颈部淋巴结切除。组织学和免疫组织化学研究显示存在嫌色型肾细胞癌和弥漫性中心细胞淋巴瘤。
嫌色组织学类型的肾细胞癌与非霍奇金淋巴瘤之间的关联非常罕见。同一患者体内出现这两种肿瘤可能给临床分期、预后预测及治疗带来问题。因此，鉴于这种情况不常见且局部期肾癌出现颈部淋巴结病时，一旦出现应怀疑这两种肿瘤可能同时存在。
