Chang M C, Ko C C, Liu C C, Douglas W H, DeLong R, Seong W-J, Hodges J, An K-N
Department of Oral Sciences, Minnesota Dental Research Center for Biomaterials and Biomechanics, University of Minnesota, 16-212 Moos Tower, 515 Delaware Street SE, Minneapolis, MN 55455, USA.
J Biomech. 2003 Aug;36(8):1209-14. doi: 10.1016/s0021-9290(03)00113-1.
Information is scarce about Young's modulus of healing bone surrounding an implant. The purpose of this preliminary study is to quantify elastic properties of pig alveolar bone that has healed for 1 month around titanium threaded dental implants, using the nanoindentation method. Two 2-year-old Sinclair miniswine were used for the study. Nanoindentation tests perpendicular to the bucco-lingual cross section were performed on harvested implant-bone blocks using the Hysitron TriboScope III. Nomarski differential interference contrast microscopy was used to identify pyramidal indentation measurements that were from bone. Reduced moduli, averaged for all anatomical regions, were found to start low (6.17 GPa) at the interface and gradually increase (slope=0.014) to a distance of 150 microm (7.89 GPa) from the implant surface, and then flatten to a slope of 0.001 from 150 to 1500 microm (10.13 GPa). Mean reduced modulus and its relationship to distance did not differ significantly by anatomic location (e.g., coronal, middle, and apical third; P>/=0.28 for all relevant tests) at 1 month after implantation.
关于种植体周围愈合骨的杨氏模量的信息很少。这项初步研究的目的是使用纳米压痕法量化猪牙槽骨在钛螺纹牙种植体周围愈合1个月后的弹性特性。使用了两头2岁的辛克莱小型猪进行该研究。使用Hysitron TriboScope III对收获的种植体-骨块进行垂直于颊舌横截面的纳米压痕测试。使用诺马斯基微分干涉对比显微镜来识别来自骨的金字塔形压痕测量值。发现所有解剖区域的平均约化模量在界面处开始较低（6.17 GPa），并逐渐增加（斜率 = 0.014）至距种植体表面150微米处（7.89 GPa），然后在150至1500微米处变平，斜率为0.001（10.13 GPa）。植入后1个月时，平均约化模量及其与距离的关系在解剖位置（例如，冠部、中部和根尖三分之一）上没有显著差异（所有相关测试的P≥0.28）。
