Bollwein Heinrich, Mayer Rainer, Stolla Rudolf
Department of Animal Reproduction, College of Veterinary Medicine, University of Munich, Munich 80539, Germany.
Theriogenology. 2003 Sep 1;60(4):597-605. doi: 10.1016/s0093-691x(03)00080-3.
Transrectal color Doppler sonography was used for the noninvasive investigation of uterine blood flow in five mares. Both the left and right uterine arteries were scanned to obtain blood flow velocity waveforms during two consecutive estrous cycles and two early pregnancies in each mare. Blood flow was expressed as the time-averaged maximum velocity (TAMV) and the resistance index (RI). In all pregnancies the embryonic vesicle could be detected for the first time on Day 11 (day of ovulation: Day 0). No differences in mean TAMV and RI values of both uterine arteries were observed in comparison to the corresponding days of the estrous cycle until Day 11 of pregnancy (P>0.05). From Day 11 onwards, mean TAMV values were higher and mean RI values lower in pregnant mares than in cyclic mares (P<0.05). During the estrous cycle TAMV and RI values did not differ between the right and left uterine arteries (P>0.05). From Days 15 to 29 of pregnancy, TAMV values were consistently higher and RI values lower in the uterine artery ipsilateral to the conceptus and they had a more distinct rise and decline, respectively, compared to the contralateral uterine artery (P<0.05). The variance component estimates for the effect of mare on TAMV and RI values during pregnancy were 60 and 53%, respectively, and for the effect of day of pregnancy, they were 29 and 34%, respectively (P<0.0001). Within mares there were no significant differences between the two pregnancies with regard to blood flow (P>0.05). The results show that uterine blood supply increases in mares during the second week of pregnancy compared to cyclic mares. Furthermore there are individual variations in blood flow between mares.
经直肠彩色多普勒超声用于对5匹母马的子宫血流进行无创性研究。在每匹母马的两个连续发情周期和两次早期妊娠期间，对左右子宫动脉进行扫描以获取血流速度波形。血流以时间平均最大速度（TAMV）和阻力指数（RI）表示。在所有妊娠中，首次在第11天（排卵日：第0天）检测到胚泡。在妊娠第11天之前，与发情周期的相应天数相比，未观察到两侧子宫动脉的平均TAMV和RI值有差异（P>0.05）。从第11天起，妊娠母马的平均TAMV值高于发情周期母马，平均RI值低于发情周期母马（P<0.05）。在发情周期中，左右子宫动脉的TAMV和RI值没有差异（P>0.05）。在妊娠第15至29天期间, 与对侧子宫动脉相比，与孕体同侧的子宫动脉的TAMV值持续较高，RI值较低，且它们分别有更明显的升高和下降（P<0.05）。妊娠期间母马对TAMV和RI值影响的方差成分估计分别为60%和53%，妊娠天数的影响分别为29%和34%（P<0.0001）。在母马内，两次妊娠之间的血流没有显著差异（P>0.05）。结果表明，与发情周期母马相比，妊娠母马在妊娠第二周子宫血液供应增加。此外，母马之间的血流存在个体差异。
