嗅觉障碍患者嗅觉上皮分类的重新评估。

A re-evaluation of the classification of olfactory epithelia in patients with olfactory disorders.

作者信息

Yamagishi M, Nakano Y

机构信息

Department of Otolaryngology, Niigata University School of Medicine, Japan.

出版信息

Eur Arch Otorhinolaryngol. 1992;249(7):393-9. doi: 10.1007/BF00192261.

DOI:10.1007/BF00192261

PMID:1283304

Abstract

We have previously demonstrated that human olfactory epithelia can be classified into five grades according to the degree of degeneration present in patients with various kinds of olfactory disorders. In practice, however, the occurrence of additional types of cell changes in other kinds of olfactory disorders and findings with immunohistochemical techniques have led us to re-evaluate our previous classification. In the present study, changes in olfactory epithelia from ten patients with various kinds of olfactory disorders are discussed and a revised classification is proposed. Microvillar and differentiating cells were also evaluated in the epithelium studied.

摘要

我们之前已经证明，根据各类嗅觉障碍患者中存在的退化程度，人类嗅觉上皮可分为五个等级。然而，在实际情况中，其他类型嗅觉障碍中出现的额外细胞变化类型以及免疫组织化学技术的研究结果促使我们重新评估之前的分类。在本研究中，我们讨论了10名患有各类嗅觉障碍患者的嗅觉上皮变化，并提出了修订后的分类。同时，我们还对所研究上皮中的微绒毛细胞和分化细胞进行了评估。