Yamagishi M, Hasegawa S, Nakano Y
Department of Otolaryngology, Niigata University School of Medicine, Japan.
Arch Otorhinolaryngol. 1988;245(5):316-20. doi: 10.1007/BF00464640.
To determine objectively the degree of olfactory disturbance, we biopsied the olfactory mucosa from patients who complained of anosmia. The olfactory disturbances in this study were caused by choanal atresia, chronic sinusitis, viral inflammation, and head trauma, as well as by congenital and idiopathic anosmia. The biopsy specimens were examined by light microscopy and the degree of mucosal degeneration present was classified according to five grades. The clinical courses of the patients studied paralleled the changes found in the olfactory mucosa.
为了客观地确定嗅觉障碍的程度，我们对主诉嗅觉丧失的患者的嗅黏膜进行了活检。本研究中的嗅觉障碍由后鼻孔闭锁、慢性鼻窦炎、病毒感染、头部外伤以及先天性和特发性嗅觉丧失引起。活检标本通过光学显微镜检查，并根据五个等级对存在的黏膜变性程度进行分类。所研究患者的临床病程与嗅黏膜中发现的变化一致。
