嗅觉障碍患者嗅黏膜的免疫组织化学检查

Immunohistochemical examination of olfactory mucosa in patients with olfactory disturbance.

作者信息

Yamagishi M, Nakamura H, Suzuki S, Hasegawa S, Nakano Y

机构信息

Department of Otolaryngology, Niigata University School of Medicine, Japan.

出版信息

Ann Otol Rhinol Laryngol. 1990 Mar;99(3 Pt 1):205-10.

PMID:1689979

Abstract

The olfactory mucosa was examined by immunohistochemistry in patients with olfactory disturbance: anosmia due to choanal atresia and chronic sinusitis, early-stage common cold, late-stage common cold, and head trauma. The results indicate that the olfactory mucosa of patients with olfactory disturbance shows specific kinds of immunoreactive patterns and that immunohistochemistry is useful for examining the degree of degeneration of pathologic human olfactory mucosa and for clarification of prognosis.

摘要

通过免疫组织化学方法对嗅觉障碍患者的嗅黏膜进行了检查，这些患者包括因后鼻孔闭锁和慢性鼻窦炎导致的嗅觉丧失、感冒早期、感冒后期以及头部外伤患者。结果表明，嗅觉障碍患者的嗅黏膜呈现出特定类型的免疫反应模式，并且免疫组织化学对于检查病理性人类嗅黏膜的退化程度以及明确预后是有用的。