Thewes Belinda, Meiser Bettina, Rickard Judy, Friedlander Michael
Department of Medical Oncology, Prince of Wales Hospital, Sydney, NSW, Australia.
Psychooncology. 2003 Jul-Aug;12(5):500-11. doi: 10.1002/pon.685.
The use of chemotherapy and endocrine therapies in the treatment of pre-menopausal women carries with it reproductive and gynaecological implications which younger women may find both unpleasant and discordant with plans for childbearing. This study aims to investigate the fertility- and menopause-related information needs of younger women with a diagnosis of early breast cancer. A retrospective qualitative methodology was chosen. Twenty-four women aged between 26 and 45 years at diagnosis participated in focus group interviews and telephone interviews. Many women thought that the information they had received in the past about fertility and menopausal symptoms was either insufficient or unavailable. Some women felt that, while information on fertility and menopause issues had not been paramount at the time of diagnosis, it became increasingly important after diagnosis. Participants spoke about the need to revisit or review fertility- and menopause-related information with their doctors during the course of treatment. Many women believed that information about fertility should be given prior to or during treatment decision-making, and that information related to the management of menopausal symptoms should be delivered during or after treatment when menopausal symptoms begin. Consultation with a fertility and/or menopause specialist-rated as the most preferred mode of receiving fertility- and menopause-related information. Clinical implications are drawn from the results of this study to assist clinicians and researchers to improve their communication with younger patients about the fertility- and menopause-related side effects of breast cancer treatment.
对绝经前女性使用化疗和内分泌疗法会带来生殖和妇科方面的影响，年轻女性可能会觉得这些影响令人不适，且与生育计划不一致。本研究旨在调查被诊断为早期乳腺癌的年轻女性在生育和绝经方面的信息需求。研究采用了回顾性定性研究方法。24名确诊时年龄在26至45岁之间的女性参与了焦点小组访谈和电话访谈。许多女性认为，她们过去收到的关于生育和更年期症状的信息要么不足，要么根本没有。一些女性觉得，虽然生育和更年期问题的信息在确诊时并非至关重要，但在确诊后变得越来越重要。参与者谈到在治疗过程中需要与医生重新讨论或回顾与生育和更年期相关的信息。许多女性认为，关于生育的信息应在治疗决策前或治疗期间提供，而与更年期症状管理相关的信息应在更年期症状出现时的治疗期间或治疗后提供。咨询生育和/或更年期专家被认为是获取生育和更年期相关信息的最优选方式。本研究结果得出了临床启示，以帮助临床医生和研究人员改善他们与年轻患者就乳腺癌治疗的生育和更年期相关副作用进行的沟通。
