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锝99m HDP在心脏淀粉样变中的摄取情况。

Uptake of technetium 99m HDP in cardiac amyloidosis.

作者信息

Kulhanek Jan, Movahed Assad

机构信息

Section of Cardiology, William S. Middleton VAMC, USA.

出版信息

Int J Cardiovasc Imaging. 2003 Jun;19(3):225-7. doi: 10.1023/a:1023608115278.

DOI:10.1023/a:1023608115278
PMID:12834159
Abstract

We present a report and a brief summary of literature focused on a patient with suspected cardiac amyloidosis from transthoracic echocardiography and tc-99m HDP scintigraphy. Imaging demonstrated significantly increased uptake of the bone tracer within the myocardium in comparison to the highest skeletal uptake. Literature described several cases of abnormal myocardial uptake of various imaging tracers in various disease states.

摘要

我们报告了一例经胸超声心动图和锝-99m 亚甲基二膦酸盐（Tc-99m HDP）闪烁扫描怀疑患有心脏淀粉样变性的患者，并对相关文献进行了简要综述。影像学检查显示，与骨骼最高摄取相比，心肌内骨显像剂摄取显著增加。文献报道了多种疾病状态下各种显像剂心肌摄取异常的几例病例。

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Uptake of technetium 99m HDP in cardiac amyloidosis.锝99m HDP在心脏淀粉样变中的摄取情况。
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2
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Medicine (Baltimore). 2020 Jan;99(4):e18905. doi: 10.1097/MD.0000000000018905.
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Expert Consensus Recommendations for the Suspicion and Diagnosis of Transthyretin Cardiac Amyloidosis.专家共识建议：疑似转甲状腺素蛋白心脏淀粉样变性的诊断。
Circ Heart Fail. 2019 Sep;12(9):e006075. doi: 10.1161/CIRCHEARTFAILURE.119.006075. Epub 2019 Sep 4.
3
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本文引用的文献

1
Myocardial Tc-99m MDP uptake on a bone scan in senile systemic amyloidosis with cardiac involvement.老年系统性淀粉样变累及心脏时，骨扫描上心肌对锝-99m亚甲基二膦酸盐的摄取情况。
Clin Nucl Med. 2000 Oct;25(10):826-7. doi: 10.1097/00003072-200010000-00019.
2
Extraosseous uptake of Tc-99m HDP in muscular dystrophy.肌营养不良症中锝-99m亚甲基二膦酸盐的骨外摄取。
Clin Nucl Med. 2000 Feb;25(2):135-6. doi: 10.1097/00003072-200002000-00013.
3
Tc-99m HDP uptake in cardiac amyloidosis.锝-99m亚甲基二膦酸盐在心脏淀粉样变性中的摄取
转甲状腺素蛋白心脏淀粉样变患者左心室心肌 Tc-HMDP 摄取的尖峰保留模式。
J Nucl Cardiol. 2018 Dec;25(6):2072-2079. doi: 10.1007/s12350-017-0894-z. Epub 2017 Apr 26.
4
Fluorine sodium fluoride positron emission tomography, a potential biomarker of transthyretin cardiac amyloidosis.氟[18F]去铁胺正电子发射断层扫描，转甲状腺素蛋白心脏淀粉样变的一个潜在生物标志物。
J Nucl Cardiol. 2018 Oct;25(5):1559-1567. doi: 10.1007/s12350-017-0799-x. Epub 2017 Feb 7.
5
Early-phase myocardial uptake intensity of Tc-HMDP vs Tc-DPD in patients with hereditary transthyretin-related cardiac amyloidosis.遗传性转甲状腺素蛋白相关心脏淀粉样变性患者 Tc-HMDP 与 Tc-DPD 的早期心肌摄取强度。
J Nucl Cardiol. 2018 Feb;25(1):217-222. doi: 10.1007/s12350-016-0707-9. Epub 2016 Nov 1.
6
[18F]-NaF PET/CT imaging in cardiac amyloidosis.[18F]-氟化钠正电子发射断层显像/计算机断层扫描成像在心脏淀粉样变中的应用
J Nucl Cardiol. 2016 Aug;23(4):846-9. doi: 10.1007/s12350-015-0287-0. Epub 2015 Sep 24.
7
(99m)Tc-HMDP scintigraphy rectifies wrong diagnosis of AL amyloidosis.锝-99m亚甲基二膦酸盐闪烁扫描术纠正了AL型淀粉样变性的误诊。
J Nucl Cardiol. 2015 Aug;22(4):853-7. doi: 10.1007/s12350-015-0176-6. Epub 2015 May 22.
8
Diffuse Myocardial Uptake of (99m)Tc-HDP in Multiple Myeloma.多发性骨髓瘤中（99m）Tc-HDP的弥漫性心肌摄取
Nucl Med Mol Imaging. 2013 Sep;47(3):208-11. doi: 10.1007/s13139-013-0209-5. Epub 2013 May 18.
9
Usefulness and limitations of 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathy.99mTc-3,3-二膦基-1,2-丙二羧酸闪烁显像在淀粉样变性心肌病病因诊断中的作用及局限性。
Eur J Nucl Med Mol Imaging. 2011 Mar;38(3):470-8. doi: 10.1007/s00259-010-1642-7. Epub 2010 Nov 11.
10
Nuclear imaging in cardiac amyloidosis.心脏淀粉样变的核成像
Eur J Nucl Med Mol Imaging. 2009 Apr;36(4):702-14. doi: 10.1007/s00259-008-1037-1. Epub 2009 Jan 21.
Clin Nucl Med. 1999 Mar;24(3):156-8. doi: 10.1097/00003072-199903000-00002.
4
Scintigraphic imaging and turnover studies with iodine-131 labelled serum amyloid P component in systemic amyloidosis.系统性淀粉样变性中使用碘-131标记血清淀粉样蛋白P成分的闪烁成像和周转率研究。
Eur J Nucl Med. 1998 Jul;25(7):701-8. doi: 10.1007/s002590050272.
5
Cardiac and pleuropulmonary AL amyloid imaging with technetium-99m labelled aprotinin.用99m锝标记抑肽酶进行心脏和胸膜肺AL淀粉样变成像。
Eur J Nucl Med. 1995 Dec;22(12):1393-401. doi: 10.1007/BF01791147.
6
Cardiac amyloidosis--diagnosis by 2-dimensional echocardiography.心脏淀粉样变性——二维超声心动图诊断
Ann Acad Med Singap. 1982 Jan;11(1):98-100.
7
Visualization of a malignant pericardial effusion with Tc-99m-EHDP.用锝-99m-亚甲基二膦酸盐显像恶性心包积液。
Clin Nucl Med. 1980 May;5(5):210-2. doi: 10.1097/00003072-198005000-00006.
8
Intense myocardial uptake of Tc-99m-MDP in a case of hypercalcemia.高钙血症病例中Tc-99m-MDP的心肌摄取增强。
Clin Nucl Med. 1981 Dec;6(12):565-7. doi: 10.1097/00003072-198112000-00001.
9
Soft-tissue uptake of 99mTc-diphosphonate in systemic AL amyloidosis.99mTc-二膦酸盐在系统性AL淀粉样变性中的软组织摄取。
Eur J Nucl Med. 1984;9(12):538-41. doi: 10.1007/BF00256851.
10
Identification of rhabdomyolysis with technetium-99m HDP bone imaging.利用锝-99m HDP骨显像识别横纹肌溶解症。
Clin Nucl Med. 1985 Nov;10(11):823. doi: 10.1097/00003072-198511000-00021.