小儿外伤性黄斑裂孔患者行玻璃体腔注射血小板浓缩液的长期效果。
Long-term results following pars plana vitrectomy with platelet concentrate in pediatric patients with traumatic macular hole.
作者信息
Wachtlin Joachim, Jandeck Claudia, Potthöfer Simone, Kellner Ulrich, Foerster Michael H
机构信息
Department of Ophthalmology, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin, Germany.
出版信息
Am J Ophthalmol. 2003 Jul;136(1):197-9. doi: 10.1016/s0002-9394(03)00105-3.
PURPOSE
To describe the long-term clinical course in children with a traumatic macular hole after vitrectomy with platelet concentrate.
DESIGN
Interventional case series.
METHODS
Four pediatric patients with a mean age of 13.2 years (range, 10-15 years) underwent pars plana vitrectomy with platelet concentrate, internal limiting membrane peeling, and SF6 gas tamponade for stage 3 traumatic macular hole repair.
RESULTS
Primary closure was achieved by a single intervention in all patients with a marked visual improvement of three to seven lines after surgery. The surgically achieved visual improvement remained stable and no vision-threatening complications occurred during the mean follow up of 35.2 months (range, 27-51 months).
CONCLUSION
We regard pars plana vitrectomy with platelet concentrate and SF6 gas instillation as safe and effective and, therefore, as the therapy of choice for traumatic macular holes particularly in children after a period of observation no longer than 3 to 4 months.
目的
描述采用浓缩血小板玻璃体切割术治疗外伤性黄斑裂孔患儿的长期临床病程。
设计
干预性病例系列。
方法
4例平均年龄13.2岁（范围10 - 15岁）的儿科患者接受了经睫状体平坦部玻璃体切割术，术中使用浓缩血小板、内界膜剥除，并注入SF6气体以修复3期外伤性黄斑裂孔。
结果
所有患者均通过单次干预实现了一期闭合，术后视力显著提高了三至七行。手术获得的视力改善保持稳定，在平均35.2个月（范围27 - 51个月）的随访期间未发生威胁视力的并发症。
结论
我们认为采用浓缩血小板和注入SF6气体的经睫状体平坦部玻璃体切割术安全有效，因此，对于外伤性黄斑裂孔，尤其是儿童患者，在观察期不超过3至4个月后，该术式为首选治疗方法。
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