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Pyranose oxidase identified as a member of the GMC oxidoreductase family.

作者信息

Albrecht Mario, Lengauer Thomas

机构信息

Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrücken, Germany.

出版信息

Bioinformatics. 2003 Jul 1;19(10):1216-20. doi: 10.1093/bioinformatics/btg140.

DOI:10.1093/bioinformatics/btg140
PMID:12835264
Abstract

Fungal pyranose oxidase is a flavoenzyme whose preferred substrate among several monosaccharides is D-glucose. After a comprehensive analysis of conserved features in a structure-based multiple sequence alignment of homologous proteins, we could classify this enzyme into the GMC oxidoreductase family. The identified homology also suggests a three-dimensional protein structure similar to the functionally related glucose oxidase.

摘要

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