Blokh Ilya, Oiseth Stanley J, Fuks Joachim, Jain Dharamuir, Eapen Saji, Koulova Lydia, Alexandrescu Doru, Li Yuan-Yi, Dutcher Janice, Wiernik Peter H
Department of Internal Medicine, Long Island Jewish Hospital, New Hyde Park, NY, USA.
Med Oncol. 2003;20(2):189-94. doi: 10.1385/MO:20:2:189.
Choriocarcinoma is a highly aggressive beta-subunit of human chorionic gonadotropin (betaHCG)-producing germ cell tumor. In men, it is a rare neoplasm and can arise in the testes or in various extragonadal locations such as the retroperitoneum, mediastinum, and pineal body. We present a highly unusual case of a middle-aged man with primary metastatic betaHCG-producing choriocarcinoma of the right thigh along with right lower-extremity venous thrombosis. We comment on prognostic variables as well as discuss several theories to account for the unusual location of his choriocarcinoma.
绒毛膜癌是一种产生人绒毛膜促性腺激素β亚基(β-HCG)的高侵袭性生殖细胞肿瘤。在男性中,它是一种罕见的肿瘤,可发生于睾丸或各种性腺外部位,如腹膜后、纵隔和松果体。我们报告一例非常罕见的病例,一名中年男性患有原发性转移性右大腿产生β-HCG的绒毛膜癌,并伴有右下肢静脉血栓形成。我们对预后变量进行了评论,并讨论了几种理论来解释他的绒毛膜癌的不寻常位置。