HIV-1发病机制。
HIV-1 pathogenesis.
作者信息
Stevenson Mario
机构信息
Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Biotech 2, Suite 319, Worcester, Massachusetts 01605, USA.
出版信息
Nat Med. 2003 Jul;9(7):853-60. doi: 10.1038/nm0703-853.
PMID:12835705
Abstract
Despite considerable advances in HIV science in the past 20 years, the reason why HIV-1 infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains elusive. A deeper understanding of the interplay between HIV-1 and its host and why simian immunodeficiency virus (SIV) is nonpathogenic in some natural hosts may provide a few answers.
摘要
尽管在过去20年里，HIV科学取得了长足进展，但HIV-1感染具有致病性的原因仍存在争议，根除HIV-1感染的目标仍然难以实现。深入了解HIV-1与其宿主之间的相互作用，以及为什么猿猴免疫缺陷病毒（SIV）在某些天然宿主中无致病性，可能会提供一些答案。
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