桦木醇、桦木酸和桦酮酸对某些包膜病毒和非包膜病毒的抗病毒活性。

Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses.

作者信息

Pavlova N I, Savinova O V, Nikolaeva S N, Boreko E I, Flekhter O B

机构信息

Belarussian Research Institute for Epidemiology and Microbiology, 4 K Zetkin str, Minsk 220050, Belarus.

出版信息

Fitoterapia. 2003 Jul;74(5):489-92. doi: 10.1016/s0367-326x(03)00123-0.

DOI:10.1016/s0367-326x(03)00123-0

PMID:12837369

Abstract

Antiviral properties of betulin, betulinic and betulonic acids were investigated in cell cultures infected with herpes simplex type I, influenza FPV/Rostock and ECHO 6 viruses. All studied triterpenes were active against herpes simplex virus. Betulin and especially betulinic acid also suppressed ECHO 6 virus reproduction.

摘要

在感染单纯疱疹病毒I型、流感病毒FPV/罗斯托克株和埃可病毒6型的细胞培养物中研究了桦木醇、桦木酸和桦木酮酸的抗病毒特性。所有研究的三萜类化合物对单纯疱疹病毒均有活性。桦木醇，尤其是桦木酸也抑制埃可病毒6型的繁殖。