Günhan O, Evren G, Demiriz M, Can C, Celasun B, Finci R
Department of Pathology, Gülhane Military Medical Academy and Medical School, Ankara, Turkey.
J Nihon Univ Sch Dent. 1992 Dec;34(4):240-8. doi: 10.2334/josnusd1959.34.240.
The distribution of S-100 protein, epithelial membrane antigen, carcinoembryonic antigen and alpha fetoprotein was studied in 38 primary salivary gland tumors. S-100 protein, a useful marker of myoepithelial cells, was demonstrated in some benign tumors. Carcinoembryonic antigen expression was consistently positive in adenoid cystic carcinoma. Demonstration of epithelial membrane antigen helped to confirm the epithelial nature of some neoplastic cells. Alpha fetoprotein was not expressed in any of the cases examined. No correlation was found between immunopositivity and tumor behavior in the present series.
对38例原发性涎腺肿瘤进行了S-100蛋白、上皮膜抗原、癌胚抗原和甲胎蛋白分布的研究。S-100蛋白是肌上皮细胞的一种有用标志物，在一些良性肿瘤中呈阳性。癌胚抗原在腺样囊性癌中始终呈阳性表达。上皮膜抗原的检测有助于证实一些肿瘤细胞的上皮性质。在所检查的所有病例中均未检测到甲胎蛋白表达。在本研究系列中，未发现免疫阳性与肿瘤行为之间存在相关性。
