从半转运RNA到转运RNA、核糖体RNA以及早期肽合成RNA分子的进化。
Evolution from semi-tRNA to tRNAs, rRNAs and an early peptide-synthesizing RNA molecule.
作者信息
Ohnishi K
机构信息
Department of Biology, Faculty of Science, Niigata University, Japan.
出版信息
Nucleic Acids Symp Ser. 1992(27):145-6.
PMID:1283904
Abstract
tRNA was found to have emerged by tandem duplication of a ca. 37-base RNA ("semi-tRNA"). The most ancestral anticodon was "(5')CCA(3')". The peptidyltransferase (PT) region of 23S rRNA was concluded to be a 5S rRNA homologue. Important evidences were obtained for elucidating that the RNA transcript from the Bacillus subtilis (BSU) trrnD operon is a relic of an early peptide-synthesizing ribozyme.
摘要
发现转运RNA（tRNA）是由一段约37个碱基的RNA（“半tRNA”）串联重复产生的。最原始的反密码子是“(5')CCA(3')”。23S核糖体RNA的肽基转移酶（PT）区域被认为是5S核糖体RNA的同源物。获得了重要证据，以阐明来自枯草芽孢杆菌（BSU）trrnD操纵子的RNA转录本是早期肽合成核酶的遗迹。
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