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[1974 - 1998年北京市首都钢铁公司基于工作场所的心血管疾病干预效果评估]

[An evaluation on effectiveness of worksite-based intervention for cardiovascular disease during 1974 - 1998 in capital iron and steel company of Beijing].

作者信息

Wu Xi-gui, Gu Dong-feng, Wu Yang-feng, Yu Xue-hai, Wang Shu-yu, Wang Nan, Gao Jiu-ming, Duan Xiu-fang, Zhou Bei-fan, Liu Li-sheng

机构信息

Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2003 Mar;37(2):93-7.

Abstract

OBJECTIVE

To explore the feasibility and effectiveness of worksite-based cardiovascular disease (CVD) prevention and control program in urban population of China.

METHODS

Worksite-based intervention program was implemented 110 000 employees at Capital Iron and Steel Company of Beijing (CISC) focusing on primary prevention for CVD and control of hypertension. Intervention components comprised of infrastructure setting-up, health education and health promotion, professional training, detection and management of hypertensive patients, and reasonably readjusting their diet structure focusing on salt intake reduction, reducing their overweight, quitting smoking, and restricting alcohol consumption in high-risk population. Changes in level of risk factors, incidence and mortality of stroke and coronary events and their trend were evaluated between the intervention group at CISC and eight simultaneously parallel reference groups in other provinces outside Beijing with population surveillance data.

RESULTS

Major risk factors for CVD, including blood pressure, body mass index and serum cholesterol level, decreased relatively in intervention population at CISC during 1974 to 1998, while those in majority of eight parallel reference groups at different provinces of China significantly increased at the same time. Systolic blood pressure (SBP) decreased by 0.8 mm Hg and 4 mm Hg in average for men and women, respectively, and their diastolic blood pressure (DBP) remained the same as baseline for both men and women at CISC, while SBP increased by (2 - 11) mm Hg and (6 - 8) mm Hg in average for men and women, respectively in reference groups, and DBP increased by (2 - 6) mm Hg in average for men in five of eight reference groups, and by (3 - 6) mm Hg for women in four of eight reference groups. Serum level of cholesterol decreased by 0.26 mmol/L in women and slightly increased for men at CISC, and increased by (0.35 - 0.97) mmol/L for men and (0.29 - 1.05) mmol/L for women in all reference groups. Prevalence of overweight increased by 58.7% for men and 11.3% for women at CISC and increased by one to 22 folds in eight reference groups. Awareness of health knowledge improved significantly with an average net reduction of SBP/DBP of (2.5/2.2) mm Hg in the enforced intervention group at CISC than that in general intervention groups. Incidence and mortality rates of stroke decreased by 54.7% and 74.3%, respectively in intervention group at CSIC, but those of coronary events slowly increased with fluctuation.

CONCLUSION

Worksite-based comprehensive intervention for CVD prevention and control was feasible and cost-effective in decreasing risk factors for CVD, incidence and mortality rate of stroke in population of urban areas of China.

摘要

目的

探讨在中国城市人群中开展基于工作场所的心血管疾病(CVD)防控项目的可行性和有效性。

方法

在北京首都钢铁公司(首钢)对110000名员工实施基于工作场所的干预项目,重点是CVD的一级预防和高血压控制。干预内容包括基础设施建设、健康教育与健康促进、专业培训、高血压患者的检测与管理,以及合理调整饮食结构,重点是减少盐摄入、减轻超重、戒烟和限制高危人群的酒精消费。利用人群监测数据,评估首钢干预组与北京以外其他省份的8个同步平行参照组之间危险因素水平、中风和冠心病事件的发病率及死亡率的变化及其趋势。

结果

1974年至1998年期间,首钢干预人群中CVD的主要危险因素,包括血压、体重指数和血清胆固醇水平相对下降,而中国不同省份的8个平行参照组中的大多数危险因素同时显著上升。首钢男性和女性的收缩压(SBP)平均分别下降了0.8 mmHg和4 mmHg,舒张压(DBP)在首钢男性和女性中均维持在基线水平,而参照组中男性和女性的SBP平均分别上升了(2 - 11)mmHg和(6 - 8)mmHg,8个参照组中有5个组男性的DBP平均上升了(2 - 6)mmHg,8个参照组中有4个组女性的DBP平均上升了(3 - 6)mmHg。首钢女性血清胆固醇水平下降了0.26 mmol/L,男性略有上升,所有参照组中男性血清胆固醇水平上升了(0.35 - 0.97)mmol/L,女性上升了(0.

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