Petersson Per, Waldenström Alexandra, Fåhraeus Christer, Schouenborg Jens
Section for Neurophysiology, Department of Physiological Sciences, BMC F10, Lund University, S-221 84 Lund, Sweden.
Nature. 2003 Jul 3;424(6944):72-5. doi: 10.1038/nature01719.
During development, information about the three-dimensional shape and mechanical properties of the body is laid down in the synaptic connectivity of sensorimotor systems through unknown adaptive mechanisms. In spinal reflex systems, this enables the fast transformation of complex sensory information into adequate correction of movements. Here we use a computer simulation to show that an unsupervised correlation-based learning mechanism, using spontaneous muscle twitches, can account for the functional adaptation of the withdrawal reflex system. We also show that tactile feedback resulting from spontaneous muscle twitches during sleep does indeed modify sensorimotor transformation in young rats in a predictable manner. The results indicate that these twitches, corresponding to human fetal movements, are important in spinal self-organization.
在发育过程中，关于身体三维形状和力学特性的信息通过未知的适应性机制被编码在感觉运动系统的突触连接中。在脊髓反射系统中，这使得复杂的感觉信息能够快速转化为对运动的适当校正。在这里，我们通过计算机模拟表明，一种基于无监督相关性的学习机制，利用自发肌肉抽搐，能够解释退缩反射系统的功能适应性。我们还表明，睡眠期间自发肌肉抽搐产生的触觉反馈确实以可预测的方式改变了幼鼠的感觉运动转换。结果表明，这些与人类胎儿运动相对应的抽搐在脊髓自组织中很重要。
