Neuman Paul, Hulth Anders, Lindén Bjarne, Johnell Olof, Dahlberg Leif
Department of Orthopedics, Malmö University Hospital, 205 02 Malmö, Sweden.
Int Orthop. 2003;27(5):262-6. doi: 10.1007/s00264-003-0485-2. Epub 2003 Jul 3.
We studied the appearance and frequency of the medial epiarticular osteophyte in human femoral heads. Specimens were sampled from 24 men and 31 women who underwent total hip arthroplasty. On radiography, medial epiarticular osteophytes were present in two thirds of the cases. However, histological examination revealed endochondral ossification in all. Presumably, the bone formation was preceded by the formation of canals and cavities containing vessels. Due to the ossification around these canals and cavities, the histological picture frequently featured two layers of cartilage with bone in the middle. Also in the marginal osteophytes, bone was formed by endochondral ossification. However, this bone appeared more irregular. The new bone formation most likely indicates a reactivated growth as an attempt to repair the osteoarthritic lesions rather than a process of degradation.
我们研究了人类股骨头内侧关节旁骨赘的外观和发生率。样本取自24名男性和31名接受全髋关节置换术的女性。在X线片上，三分之二的病例存在内侧关节旁骨赘。然而，组织学检查显示所有病例均有软骨内成骨。据推测，骨形成之前先形成了含有血管的管道和腔隙。由于这些管道和腔隙周围的骨化，组织学图像常常呈现两层软骨中间夹着骨组织的特征。同样，在边缘骨赘中，也是通过软骨内成骨形成骨组织。然而，这种骨组织看起来更不规则。新骨形成很可能表明是一种重新激活的生长过程，是试图修复骨关节炎病变，而非退变过程。
