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用于鉴定成骨细胞分化转录调节因子的基因组方法。

Genomic approaches to identifying transcriptional regulators of osteoblast differentiation.

作者信息

Stains Joseph P, Civitelli Roberto

机构信息

Division of Bone and Mineral Diseases, Department of Internal Medicine, Barnes-Jewish Hospital, North Campus, 216 S, Kingshighway Blvd, St, Louis, MO 63110, USA.

出版信息

Genome Biol. 2003;4(7):222. doi: 10.1186/gb-2003-4-7-222. Epub 2003 Jul 1.

DOI:10.1186/gb-2003-4-7-222
PMID:12844353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC193624/
Abstract

Recent microarray studies of mouse and human osteoblast differentiation in vitro have identified novel transcription factors that may be important in the establishment and maintenance of differentiation. These findings help unravel the pattern of gene-expression changes that underly the complex process of bone formation.

摘要

最近关于小鼠和人类成骨细胞体外分化的微阵列研究已经鉴定出了一些新的转录因子，这些转录因子可能在分化的建立和维持过程中发挥重要作用。这些发现有助于揭示构成骨形成这一复杂过程基础的基因表达变化模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95d0/193624/e2ab933441a8/gb-2003-4-7-222-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95d0/193624/e2ab933441a8/gb-2003-4-7-222-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95d0/193624/e2ab933441a8/gb-2003-4-7-222-1.jpg

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Transcriptional profiling of human osteoblast differentiation.人类成骨细胞分化的转录谱分析。
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