结直肠癌的放射免疫检测

Radioimmunodetection of colorectal carcinoma.

作者信息

Artiko V, Obradovic V, Davidovic B, Petrovic N, Petrovic M, Krivokapic Z, Kecmanovic D, Pesko P, Djukic V, Milosavljevic T, Adanja G, Vlajkovic M

机构信息

Institute for Nuclear Medicine, Clinical Center of Serbia, Visegradska 26, 11 000 Belgrade, Yugoslavia.

出版信息

Hepatogastroenterology. 2003 Jul-Aug;50(52):1029-31.

PMID:12845972

Abstract

BACKGROUND/AIMS: The aim of the study is detection of the recurrences and metastases of colorectal carcinomas using 111In-labeled antibodies B72.3.

METHODOLOGY

Fourteen patients underwent planar immunoscintigraphy and/or tomoscintigraphy.

RESULTS

With tomography in comparison to planar scintigraphy, we can access better distinction of tumor and estimation of its size. Other imaging methods (computed tomography, ultrasonography) have an advantage in detection of liver metastases, while immunoscintigraphy is more specific for the assessment of malignant abdominal tumors and extrahepatic metastases.

CONCLUSIONS

The first results point out that Oncoscint CR-103 can be useful in diagnosis of recurrences and metastases of colorectal carcinoma, viability assessment after radiotherapy and in the choice of the adequate surgical treatment in dependence of the spread of the disease.

摘要

背景/目的：本研究旨在使用铟-111标记的抗体B72.3检测结直肠癌的复发和转移。