Artiko V, Obradovic V, Davidovic B, Petrovic N, Petrovic M, Krivokapic Z, Kecmanovic D, Pesko P, Djukic V, Milosavljevic T, Adanja G, Vlajkovic M
Institute for Nuclear Medicine, Clinical Center of Serbia, Visegradska 26, 11 000 Belgrade, Yugoslavia.
Hepatogastroenterology. 2003 Jul-Aug;50(52):1029-31.
BACKGROUND/AIMS: The aim of the study is detection of the recurrences and metastases of colorectal carcinomas using 111In-labeled antibodies B72.3.
Fourteen patients underwent planar immunoscintigraphy and/or tomoscintigraphy.
With tomography in comparison to planar scintigraphy, we can access better distinction of tumor and estimation of its size. Other imaging methods (computed tomography, ultrasonography) have an advantage in detection of liver metastases, while immunoscintigraphy is more specific for the assessment of malignant abdominal tumors and extrahepatic metastases.
The first results point out that Oncoscint CR-103 can be useful in diagnosis of recurrences and metastases of colorectal carcinoma, viability assessment after radiotherapy and in the choice of the adequate surgical treatment in dependence of the spread of the disease.
背景/目的：本研究旨在使用铟-111标记的抗体B72.3检测结直肠癌的复发和转移。
14例患者接受了平面免疫闪烁显像和/或断层闪烁显像。
与平面闪烁显像相比，断层显像能更好地区分肿瘤并估计其大小。其他成像方法（计算机断层扫描、超声检查）在检测肝转移方面具有优势，而免疫闪烁显像在评估腹部恶性肿瘤和肝外转移方面更具特异性。
初步结果表明，癌闪烁显像剂CR-103可用于诊断结直肠癌的复发和转移、放疗后的生存能力评估以及根据疾病扩散情况选择合适的手术治疗方案。
