Robins Perry
New York University Medical Center, 530 First Avenue, New York, NY 10016, USA.
J Drugs Dermatol. 2002 Jul;1(1):25-30.
Pulse therapy has been used for many years, but rarely in a clinical setting. This article describes a clinical study designed to determine the efficacy of pulse therapy with 5-FU for patients with multiple actinic keratoses. The results indicated that pulse therapy was indeed effective in eradicating most of the actinic keratoses while causing less discomfort or disfigurement than the FDA recommended dose, especially for patients with less severe and milder forms of actinic keratoses.
脉冲疗法已经使用多年，但在临床环境中很少使用。本文描述了一项临床研究，旨在确定5-氟尿嘧啶脉冲疗法对多发性光化性角化病患者的疗效。结果表明，脉冲疗法确实能有效根除大多数光化性角化病，同时与美国食品药品监督管理局推荐剂量相比，引起的不适或容貌损伤更少，尤其是对于病情较轻和较温和形式的光化性角化病患者。
