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[基于新型国际临床化学和检验医学联合会(IFCC)参考物质CRM 470的突尼斯人群9种血浆蛋白参考范围]

[Reference ranges of 9 plasmatic proteins in Tunisian population based on the new IFCC reference material CRM 470].

作者信息

Znazen Raja, Ben Ayed Mourad, Gargouri Jalel, Bel Hadj Hmida Youssef, Kassis Mondher, Damak Jamel, Masmoudi Hatem

机构信息

Laboratoire d'Immunologie, CHU Habib Bourguiba de Sfax.

出版信息

Tunis Med. 2003 Apr;81(4):264-9.

PMID:12848010
Abstract

The interpretation of biological exam results requires the knowledge of physiological variation factors and reference values for every parameter. Following the preparation and the diffusion by the International Federation of Clinical Chemistry (IFCC) of a new reference material for the dosage of plasmatic proteins (CRM470) and in order to take part in the international effort of standardization of these dosages, we established reference ranges in the tunisian population for 9 plasmatic proteins: the Immunoglobulines G, A and M, complement factors C3 and C4, albumin, transferrin, haptoglobin and the a 1-glycoprotéin acid. Our sample of 211 healthy blood donors aged between 18 and 63 years. Reference limits 0.95 that we obtained are located within variation of most reference values lately found in the literature.

摘要

生物学检查结果的解读需要了解每个参数的生理变异因素和参考值。随着国际临床化学联合会(IFCC)制备并推广了一种用于血浆蛋白定量的新参考物质(CRM470),并且为了参与这些定量检测的国际标准化工作,我们在突尼斯人群中建立了9种血浆蛋白的参考范围:免疫球蛋白G、A和M、补体因子C3和C4、白蛋白、转铁蛋白、触珠蛋白和α1-酸性糖蛋白。我们的样本包括211名年龄在18至63岁之间的健康献血者。我们获得的0.95的参考限值处于最近文献中发现的大多数参考值的变异范围内。

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Tunis Med. 2003 Apr;81(4):264-9.
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