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Synthesis and biological action of 3-R-4-substituted-delta2-1,2,4-triazoline-5-thione.

作者信息

Dobosz Maria, Wujec Monika, Waśko Adam

机构信息

Department of Organic Chemistry, Faculty of Pharmacy, Medical University, 6 Staszica Str., 20-081 Lublin.

出版信息

Acta Pol Pharm. 2003 Jan-Feb;60(1):41-4.

PMID:12848366
Abstract

In the reaction of hydroiodide of methyl ester of 3-thiocarbazic acid with diethylamine and morpholine hydroiodide of 2-amino-1-substituted-guanidine [I-II] were obtained. These compounds were then converted to respective 3-R-4-substituted-delta2-1,2,4-triazoline-5-thione [III-X] in the reaction with isothiocyanates. Some of these compounds were screened for their antibacterial activities.

摘要

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