Li B Y
Department of pathology, Jilin Medical College.
Zhonghua Jie He He Hu Xi Za Zhi. 1992 Aug;15(4):204-6, 253-4.
The pulmonary interstitial fibrosis was caused by injecting Bleomycin into mouse trachea. After the injection, the volume of glycosaminoglycans (GAG) in bronchoalveolar lavage fluid and lung tissues was increased. The observation of histochemical stain and electron microscope showed that the distribution of GAG in lung tissues was varied at different time after the injection, and related to the volume of collagen proteins and the formation of pulmonary interstitial fibrosis.