Krishnakumar Subramanian, Mohan E Ravindra, Babu Kalpana, Das Dipankar, Biswas Jyotirmay
Sankara Nethralaya, Medical and Vision Research Foundations, Chennai, Tamil Nadu, India.
Surv Ophthalmol. 2003 Jul-Aug;48(4):439-46. doi: 10.1016/s0039-6257(03)00050-x.
Eccrine duct carcinoma belongs to a group of malignant sweat gland tumors showing de novo eccrine differentiation, but without features of benign adnexal counterparts. They are therefore likely to be confused with visceral adenocarcinomas that have metastasized to the lid. These tumors require important diagnostic considerations when adenocarcinoma is encountered in the lid in the absence of a known primary tumor. We present the case of a 60-year-old man with a nodule in the right upper eyelid that was histopathologically diagnosed as eccrine duct carcinoma of the lid. The differential diagnosis of eccrine carcinomas based on light microscopy, enzyme histochemistry, and immunohistochemistry is discussed, and a list of the various malignant eccrine tumors reported in the lid is presented.
小汗腺导管癌属于一组恶性汗腺肿瘤，具有原发性小汗腺分化特征，但无良性附属器肿瘤的特征。因此，它们很可能与转移至眼睑的内脏腺癌相混淆。当在眼睑出现腺癌而又无已知原发肿瘤时，对这些肿瘤进行诊断需要慎重考虑。我们报告一例60岁男性，右上眼睑有一结节，经组织病理学诊断为眼睑小汗腺导管癌。本文讨论了基于光镜、酶组织化学和免疫组织化学对小汗腺癌的鉴别诊断，并列出了眼睑中报道的各种恶性小汗腺肿瘤。
