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1,2,4-Triazolo mercapto and aminonitriles as potent antifungal agents.

作者信息

Collin Xavier, Sauleau Armelle, Coulon Joël

机构信息

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, avenue du Pr Léon Bernard, F-35043 Rennes Cedex, France.

出版信息

Bioorg Med Chem Lett. 2003 Aug 4;13(15):2601-5. doi: 10.1016/s0960-894x(03)00378-0.

Abstract

A series of 3-mercapto-1,2,4-triazoles mono or disubstituted at 2-, 3- or 4-positions were synthesized and evaluated as antifungal agents. Many of these derivatives exhibit high activity against Candida albicans and Candida tropicalis.

摘要

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