Collin Xavier, Sauleau Armelle, Coulon Joël
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, avenue du Pr Léon Bernard, F-35043 Rennes Cedex, France.
Bioorg Med Chem Lett. 2003 Aug 4;13(15):2601-5. doi: 10.1016/s0960-894x(03)00378-0.
A series of 3-mercapto-1,2,4-triazoles mono or disubstituted at 2-, 3- or 4-positions were synthesized and evaluated as antifungal agents. Many of these derivatives exhibit high activity against Candida albicans and Candida tropicalis.