在纽约市1型和2型人类嗜T淋巴细胞病毒（HTLV）血清学阴性的献血者中检测HTLV tax序列。
Detection of human T-lymphotropic virus (HTLV) tax sequences in New York City blood donors seronegative for HTLV types 1 and 2.
作者信息
Dezzutti Charlene S, Guenthner Patricia C, Daniel Sylvester, Utz Ursula, Cabrera Thania, Marshall James H, Bianco Celso, Lal Renu B, Cowan Elliot P
机构信息
Division of AIDS, STD, and TB Laboratory Research, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
出版信息
Clin Diagn Lab Immunol. 2003 Jul;10(4):715-7. doi: 10.1128/cdli.10.4.715-717.2003.
Abstract
A potential public health concern is the reported detection of the human T-lymphotropic virus (HTLV) tax gene in the lymphocytes of up to 11% of a low-risk group of New York City blood donors (NYBD). This study aimed to independently confirm the prevalence of HTLV tax sequences in 293 NYBD. All NYBD tested negative for antibodies to HTLV types 1 and 2 and HTLV Tax. HTLV tax sequences were not detected in the NYBD lymphocytes. These data demonstrate the lack of HTLV-1 tax in this group of NYBD at low risk for HTLV infection.
摘要
一个潜在的公共卫生问题是，据报道在纽约市低风险献血者群体（NYBD）中，高达11%的人的淋巴细胞中检测到人类嗜T淋巴细胞病毒（HTLV）的tax基因。本研究旨在独立确认293名NYBD中HTLV tax序列的流行情况。所有NYBD的HTLV 1型和2型抗体以及HTLV Tax检测均为阴性。在NYBD淋巴细胞中未检测到HTLV tax序列。这些数据表明，在这组HTLV感染低风险的NYBD中不存在HTLV-1 tax。
相似文献
1
Detection of human T-lymphotropic virus (HTLV) tax sequences in New York City blood donors seronegative for HTLV types 1 and 2.
Clin Diagn Lab Immunol. 2003 Jul;10(4):715-7. doi: 10.1128/cdli.10.4.715-717.2003.
2
Laboratory characterization of human T cell lymphotropic virus types 1 (HTLV-1) and 2 (HTLV-2) infections in blood donors from Sao Paulo, Brazil.
Am J Trop Med Hyg. 1997 Aug;57(2):142-8. doi: 10.4269/ajtmh.1997.57.142.
3
Human T lymphotropic virus types I and II proviral sequences in Argentinian blood donors with indeterminate Western blot patterns.
J Med Virol. 2004 Oct;74(2):323-7. doi: 10.1002/jmv.20172.
4
Estimation of the window period of human T-cell leukemia virus type 1 and 2 tests by a lookback study of seroconverters among Japanese voluntary blood donors.
Transfusion. 2021 Feb;61(2):484-493. doi: 10.1111/trf.16213. Epub 2020 Dec 24.
5
Is seroprevalence of HTLV-I/II among blood donors in India relevant?
Indian J Pathol Microbiol. 2006 Oct;49(4):532-4.
6
Human T-cell lymphotropic virus type 1 tax among American blood donors.
Clin Diagn Lab Immunol. 1998 Nov;5(6):831-5. doi: 10.1128/CDLI.5.6.831-835.1998.
7
Strategies for diagnosis of HTLV-I and -II.
Transfusion. 2002 Jun;42(6):780-91. doi: 10.1046/j.1537-2995.2002.00114.x.
8
[Confirmation of the presence in Cuba of human T-cell lymphotropic virus type I using the polymerase chain reaction].
Rev Cubana Med Trop. 1997;49(3):204-8.
9
[Sero-epidemiological study on the human T-cell leukaemia virus type I/II infection in the east coastal areas of Fujian province].
Zhonghua Liu Xing Bing Xue Za Zhi. 2004 May;25(5):428-30.
10
Difficulties in the diagnosis of HTLV-2 infection in HIV/AIDS patients from Brazil: comparative performances of serologic and molecular assays, and detection of HTLV-2b subtype.
Rev Inst Med Trop Sao Paulo. 2007 Jul-Aug;49(4):225-30. doi: 10.1590/s0036-46652007000400006.
引用本文的文献
1
Can the level of immunosuppression in human immunodeficiency virus-infected patients affect the reliability of human T-cell lymphotropic virus type 2 serological diagnosis?
Clin Vaccine Immunol. 2006 Jan;13(1):160-1. doi: 10.1128/CVI.13.1.160-161.2006.
本文引用的文献
1
Defective human T-cell leukaemia virus type 1 (HTLV-1) genomes: no evidence in serologically indeterminate german blood donors but new type detected in established cell lines.
J Med Virol. 2002 Jan;66(1):102-6. doi: 10.1002/jmv.2117.
2
Serological, epidemiological, and molecular differences between human T-cell lymphotropic virus Type 1 (HTLV-1)-seropositive healthy carriers and persons with HTLV-I Gag indeterminate Western blot patterns from the Caribbean.
J Clin Microbiol. 2001 Apr;39(4):1247-53. doi: 10.1128/JCM.39.4.1247-1253.2001.
3
Trends in incidence and prevalence of major transfusion-transmissible viral infections in US blood donors, 1991 to 1996. Retrovirus Epidemiology Donor Study (REDS).
JAMA. 2000 Jul 12;284(2):229-35. doi: 10.1001/jama.284.2.229.
4
Chimeric matrix proteins encoded by defective proviruses with large internal deletions in human T-cell leukemia virus type 1-infected humans.
J Virol. 2000 May;74(9):3933-40. doi: 10.1128/jvi.74.9.3933-3940.2000.
5
Absence of human T-lymphotropic virus type I tax sequences in a population of normal blood donors in the Baltimore, MD/Washington, DC, area: results from a multicenter study.
Transfusion. 1999 Aug;39(8):904-9. doi: 10.1046/j.1537-2995.1999.39080904.x.
6
Defective and wild-type human T-cell leukemia virus type I proviruses: characterization of gene products and trans-interactions between proviruses.
Virology. 1999 Sep 30;262(2):442-51. doi: 10.1006/viro.1999.9909.
7
HTLV-I/II seroindeterminate Western blot reactivity in a cohort of patients with neurological disease.
J Infect Dis. 1999 Sep;180(3):685-94. doi: 10.1086/314923.
8
Human T-cell lymphotropic virus type 1 tax among American blood donors.
Clin Diagn Lab Immunol. 1998 Nov;5(6):831-5. doi: 10.1128/CDLI.5.6.831-835.1998.
9
The current risk of retroviral infections transmitted by transfusion in patients who have undergone multiple transfusions. Cooleycare Cooperative Group.
Arch Intern Med. 1998 Jul 27;158(14):1566-9. doi: 10.1001/archinte.158.14.1566.
10
Defective human T-cell lymphotropic virus type I (HTLV-I) provirus in 10 Chilean seronegative patients with tropical spastic paraparesis or HTLV-I-associated myelopathy.
J Clin Microbiol. 1998 Jun;36(6):1811-3. doi: 10.1128/JCM.36.6.1811-1813.1998.
Zotero 插件