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30例大脑后动脉动脉瘤患者的治疗及预后

Treatment and outcome in 30 patients with posterior cerebral artery aneurysms.

作者信息

Taylor Christopher L, Kopitnik Thomas A, Samson Duke S, Purdy Phillip D

机构信息

Department of Neurological Surgery and Division of Neuroradiology, University of Texas Southwestern, Dallas, Texas 75390-8855, USA.

出版信息

J Neurosurg. 2003 Jul;99(1):15-22. doi: 10.3171/jns.2003.99.1.0015.

Abstract

OBJECT

The records of 30 patients with posterior cerebral artery (PCA) aneurysms treated during a 12-year period were reviewed to determine outcome and the risk of visual field deficit associated with PCA sacrifice.

METHODS

Clinical data and treatment summaries for all patients were maintained in an electronic database. The Glasgow Outcome Scale (GOS) and modified Rankin Scale (mRS) scores were determined by an independent registrar. Visual field changes were determined by review of medical records. Twenty-eight patients were treated with open surgery, one of them after an attempt at detachable coil embolization failed. Two patients underwent successful endovascular PCA sacrifice. The mean GOS and mRS scores in 18 patients with unruptured aneurysms were 4 and 2, respectively, at discharge. Subarachnoid hemorrhage (SAH) from other aneurysms and neurological deficits caused by the PCA lesion or underlying disease contributed to poor outcomes in this group. The mean GOS and mRS scores in 12 patients with ruptured aneurysms were 4 and 4, respectively, at discharge. One patient died of severe vasospasm. Neurological deficits secondary to SAH and, in one patient, treatment of a concomitant arteriovenous malformation contributed to poor outcomes in the patients with ruptured aneurysms. Seven patients with normal visual function preoperatively underwent PCA occlusion. One patient (14%) developed a new visual field deficit.

CONCLUSIONS

Optimal treatment of PCA aneurysms is performed via one of several surgical approaches or by endovascular therapy. The approach is determined, in part, by the anatomical location and size of the aneurysm and the presence of underlying disease and neurological deficits.

摘要

目的

回顾12年间30例大脑后动脉(PCA)动脉瘤患者的治疗记录,以确定手术结果以及与PCA牺牲相关的视野缺损风险。

方法

所有患者的临床资料和治疗总结均保存在电子数据库中。格拉斯哥预后量表(GOS)和改良Rankin量表(mRS)评分由独立的登记员确定。通过查阅病历确定视野变化。28例患者接受了开放手术治疗,其中1例在可脱性弹簧圈栓塞术尝试失败后进行了手术。2例患者成功进行了血管内PCA牺牲。18例未破裂动脉瘤患者出院时GOS和mRS评分的平均值分别为4分和2分。其他动脉瘤引起蛛网膜下腔出血(SAH)以及PCA病变或基础疾病导致的神经功能缺损导致该组患者预后不良。12例破裂动脉瘤患者出院时GOS和mRS评分的平均值分别为4分和4分。1例患者死于严重血管痉挛。SAH继发的神经功能缺损以及1例患者同时治疗动静脉畸形导致破裂动脉瘤患者预后不良。7例术前视力功能正常的患者接受了PCA闭塞术。1例患者(14%)出现了新的视野缺损。

结论

PCA动脉瘤的最佳治疗可通过几种手术方法之一或血管内治疗来进行。治疗方法部分取决于动脉瘤的解剖位置和大小以及基础疾病和神经功能缺损的存在情况。

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