Rafferty C N, Phillips R D, Guy A W
Electric Power Research Institute, Palo Alto, California 94303-1395.
Bioelectromagnetics. 1992;Suppl 1:1-10.
A workshop on the dosimetry of extremely-low-frequency fields was held to assess current knowledge in this field and to develop a set of recommendations for new research that meets the needs of health risk assessment, in particular, the assessment of cancer risk. The workshop was sponsored by the Electric Power Research Institute and was held on March 20-22, 1991, in Carmel, California. Major topics of the workshop were microdosimetry of induced electric fields, scaling of induced fields among biological systems from cells to humans, and the problem of defining a biologically effective "dose." A number of research recommendations were developed, the most important of which are to (1) characterize the natural background electric and magnetic fields in tissues and near cells, (2) improve experimental exposure geometries to allow accurate characterization of induced fields in samples, (3) design experiments to distinguish between electric and magnetic field mechanisms, (4) develop standard in vitro biological systems with reproducible and well-established responses to fields, and (5) develop definition of dose with respect to fields at the primary site of interaction.
举办了一次关于极低频场剂量学的研讨会,以评估该领域的现有知识,并为满足健康风险评估需求,特别是癌症风险评估需求的新研究制定一套建议。该研讨会由电力研究所在1991年3月20日至22日于加利福尼亚州卡梅尔举办。研讨会的主要议题包括感应电场的微剂量学、从细胞到人类的生物系统间感应场的尺度换算,以及定义生物有效“剂量”的问题。提出了一些研究建议,其中最重要的是:(1)描述组织和细胞附近的自然背景电场和磁场;(2)改进实验暴露几何结构,以便准确描述样品中的感应场;(3)设计实验以区分电场和磁场机制;(4)开发对场有可重复且确定反应的标准体外生物系统;(5)针对相互作用的主要部位的场制定剂量定义。