Toyoda H, Fukui K, Okabe H, Kitoh A, Iguchi I, Kanematsu I
Department of Neurosurgery, Ogaki Municipal Hospital, Japan.
No To Shinkei. 1992 Oct;44(10):929-33.
A thirty-four-year-old man was admitted to our hospital because of the disturbed visual acuity and pain on the eye movement of the right eye. He had prominent right eye and CT-scan and MRI of the brain disclosed a tumor which could be obviously distinguished from the extraocular muscles, optic nerve and the bulb of eye in the retrobulbar region. On operation we identified dark-red solid tumor which was 3.0cm in diameter, and diagnosed it malignant melanoma pathologically. Because postoperative study detected amelanotic melanoma in the white patch on the right upper extremity, this right orbital tumor was considered to be the metastasis of it from the right upper extremity. Metastatic malignant melanoma of the skin to the orbit is very rare, while most of the eye-associated malignant melanoma originates from uveal tract, special choroid, and conjunctiva. This case was the 26th case of these in the world and the first case in Japan, furthermore the 4th case in the world whose first symptoms were caused by the orbital metastasis.
一名34岁男性因右眼视力障碍和眼球运动时疼痛入院。他右眼突出，脑部CT扫描和MRI显示有一个肿瘤，在球后区域可明显与眼外肌、视神经和眼球区分开来。手术中我们发现一个直径3.0厘米的暗红色实性肿瘤，病理诊断为恶性黑色素瘤。因为术后检查在右上臂白色斑块中发现无色素性黑色素瘤，所以这个右眼眶肿瘤被认为是右上臂肿瘤转移所致。皮肤转移性恶性黑色素瘤转移至眼眶非常罕见，而大多数眼部相关恶性黑色素瘤起源于葡萄膜、特殊脉络膜和结膜。该病例是世界上第26例此类病例，日本首例，此外也是世界上第4例首发症状由眼眶转移引起的病例。
