Agargun Mehmet Y, Cartwright Rosalind
Yuzuncu Yil University School of Medicine, Department of Psychiatry, Van 65200, Turkey.
Psychiatry Res. 2003 Jul 15;119(1-2):33-9. doi: 10.1016/s0165-1781(03)00111-2.
To examine the relationship between the emotional quality of dreams, REM sleep variables and suicidal tendency in depressed individuals, 26 depressed volunteers (10 males and 16 females) were assessed with the Beck Depression Inventory (BDI) and the Hamilton Depression Rating Scale (HDRS), and underwent 3 nights of polysomnography. There was a significant negative correlation between suicidality scores and REM latency and a positive correlation between suicidality and REM percent. Suicidal subjects had a significantly shorter mean REM latency and a higher mean REM percentage than the non-suicidal subjects. As expected in normal subjects, 20 subjects had an increase in dream-like quality (DLQ) of REM reports between the first and second halves of the night. The six subjects with a negative DLQ difference also scored as suicidal. A reduction in dream-like quality of the REM content reports between the first and second halves of the night was found to be associated with suicidal tendency. The findings may indicate that these subjects fail to self-regulate mood and integrate affect into long-term memory networks during sleep. Theoretical and clinical implications of these findings in depression are discussed.
为了研究抑郁症患者梦境的情绪质量、快速眼动（REM）睡眠变量与自杀倾向之间的关系，对26名抑郁症志愿者（10名男性和16名女性）进行了贝克抑郁量表（BDI）和汉密尔顿抑郁评定量表（HDRS）评估，并进行了3晚的多导睡眠图监测。自杀倾向得分与REM潜伏期之间存在显著负相关，与REM百分比之间存在正相关。有自杀倾向的受试者的平均REM潜伏期明显短于无自杀倾向的受试者，平均REM百分比则更高。正如正常受试者所预期的那样，20名受试者在夜间前半段和后半段之间的REM报告中的梦境样质量（DLQ）有所增加。DLQ差异为负的6名受试者也被评定为有自杀倾向。研究发现，夜间前半段和后半段之间REM内容报告的梦境样质量降低与自杀倾向有关。这些发现可能表明，这些受试者在睡眠期间无法自我调节情绪并将情感整合到长期记忆网络中。本文讨论了这些发现在抑郁症中的理论和临床意义。
