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慢性鼻-鼻窦炎诊断中的成本分析

Cost analysis in the diagnosis of chronic rhinosinusitis.

作者信息

Stankiewicz James A, Chow James M

机构信息

Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, Maywood, Illinois 60153, USA.

出版信息

Am J Rhinol. 2003 May-Jun;17(3):139-42.

Abstract

BACKGROUND

The present treatment regimen for a diagnosis of chronic rhinosinusitis involves a prolonged course of antibiotic therapy along with other adjunctive therapy. The decision to start treatment is made after diagnosis of chronic rhinosinusitis, which is based on subjective symptoms. The working hypothesis of this study is that the diagnosis based on subjective symptoms is inaccurate, leading to inappropriate antibiotic therapy and unnecessary health care expense.

METHODS

One hundred patients were evaluated prospectively to determine which patients qualified for this study. Seventy-eight patients satisfied current criteria for a diagnosis of rhinosinusitis.

RESULTS

Fifty-three percent (41 patients) of the 78 patients did not have a diagnosis of chronic sinusitis based on same-day computed tomography (CT) scanning. A charge analysis comparing treatment after diagnosis with medical therapy alone and CT scan for failures versus CT scanning with medical treatment for positive scans was performed. Although the most economical method of treatment was initiating medical therapy, it was also the least sensitive and specific in that 52% of patients didn't require the treatment. Endoscopy and/or CT screening with medical therapy were much better at appropriate diagnosis and targeted therapy but charge analysis indicated a much higher cost.

CONCLUSION

Presently, the current subjective diagnostic paradigm for chronic rhinosinusitis is most cost-effective but least accurate. Objective evaluations (endoscopy and CT scanning) to aid in diagnosis are more accurate but more costly. Where cost constraints are important, careful considerations of alternatives are important.

摘要

背景

目前慢性鼻-鼻窦炎的治疗方案包括长期的抗生素治疗以及其他辅助治疗。治疗决策在基于主观症状诊断慢性鼻-鼻窦炎之后做出。本研究的工作假设是基于主观症状的诊断不准确,会导致不恰当的抗生素治疗和不必要的医疗费用。

方法

前瞻性评估了100名患者以确定哪些患者符合本研究条件。78名患者符合目前鼻-鼻窦炎的诊断标准。

结果

78名患者中53%(41名患者)根据当日计算机断层扫描(CT)结果未诊断为慢性鼻窦炎。进行了一项费用分析,比较了诊断后治疗与单纯药物治疗以及扫描结果为阴性时CT扫描与扫描结果为阳性时药物联合CT扫描的情况。虽然最经济的治疗方法是开始药物治疗,但它也是最不敏感和特异性最低的,因为52%的患者不需要这种治疗。内镜检查和/或CT筛查联合药物治疗在准确诊断和靶向治疗方面要好得多,但费用分析表明成本要高得多。

结论

目前,慢性鼻-鼻窦炎当前基于主观症状的诊断模式最具成本效益,但准确性最低。有助于诊断的客观评估(内镜检查和CT扫描)更准确,但成本更高。在成本限制很重要的情况下,仔细考虑替代方案很重要。

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